For this reason, mock communities are best used to evaluate relative performance in the context of benchmarking, rather than the absolute accuracy of a specific method [67]. Similarly, mock communities have been long recommended as positive controls in microbiome sequencing experiments [91], and ...
The incidence of young-onset colorectal cancer (yCRC) has been increasing in recent decades, but little is known about the gut microbiome of these patients. Most studies have focused on old-onset CRC (oCRC), and it remains unclear whether CRC signatures
However, although probiotic use has been greatly popularized among the general public, there are conflicting clinical results for many probiotic strains and formulations. Emerging insights from microbiome research enable an assessment of gut colonization by probiotics, strain-level activity, interactions ...
Equally important are the identification and stratification of relevant cohorts to support cross-study comparisons and consolidate research findings (e.g., The Quadram Institute website released for best practice in microbiome research [114]). Robust human studies must be conducted in real-life ...
Microbiome engineering is increasingly being employed as a solution to challenges in health, agriculture, and climate. Often manipulation involves inoculation of new microbes designed to improve function into a preexisting microbial community. Despite, i
Nutrition, the gut microbiome and the metabolic syndrome[J] . Petia Kovatcheva-Datchary,Tulika Arora.Best Practice & Research Clinical Gastroenterology . 2013 (1)Petia Kovatcheva-Datchary,Tulika Arora.Nutrition, the gut microbiome and the metabolic syndrome[J].Best Practice & Research...
The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses that performs essential functions for immune development, pathogen colonization resistance, and food metabolism. Perturbation of the gut microbiome’s ecological balance, commonly by antibiotics, can cause and exace...
and through microbial activity in our digestive systems. The 10 trillion to 100 trillion microbes that reside in our gut and their associated genomes, known as the gut microbiome, also differ between males and females. They are known to influence our immune system and may play a role in great...
J. Antibiotics as instigators of microbial dysbiosis: implications for asthma and allergy. Trends Immunol. 39, 697–711 (2018). Article CAS PubMed Google Scholar Langdon, A., Crook, N. & Dantas, G. The effects of antibiotics on the microbiome throughout development and alternative approaches...
Various omics-based biomarkers related to the occurrence, progression, and prognosis of colorectal cancer (CRC) have been identified. In this study, we attempted to identify gut microbiome-based biomarkers and detect their association with host gene expr