Placebo-controlled human studies do not show a consistent effect of antibiotic use on body weight and insulin sensitivity at a population level, but rather an individual-specific or subgroup-specific response. This response to antibiotic use is affected by the resistance and resilience of the gut ...
Continuous indiscriminate use of antibiotic drops may lead to the development of resistant strains of bacteria. Also, other strains of bacteria may proliferate if they do not fall within the sensitivity spectrum of the drops used. Systemic antibiotics become necessary when the internal or deeper struc...
In accordance to the latter, it is commonly known that patients usually develop allergic reactions when reexposed to an antibiotic [6]. When clusters 3 and 4, representing an early onset of ARA (during the first year of life), were compared to each other, somewhat different patterns were ...
A subset of SMs exhibit functions of pharmaceutical importance, such as antibacterial activity, which could address the current antibiotic resistance problem. Genome mining of under-studied microbes will contribute to the repertoire of currently known BGCs and hence SMs and will advance the finding of...
These low sensitivities may be explained by high local antibiotic concentration due to the indwelling spacer. However, Janz et al. also demonstrated a low sensitivity of SFC of 13% in 69 girdlestone hips [16]. Additionally, we found a high bacteria shift rate of 76.5%. This rate compares ...
IsoLCA mediated the association ofRuminococcaceae UCG-002andRuminococcaceae UCG-003with the risk of T2D (41.7%,pmediation = 0.040; 53.2%,pmediation < 0.001, respectively, Fig.3g, h). Sensitivity analysis for mediation effects indicated that the results of the above mediation analysi...
The recent outbreak of the Coronavirus pandemic resulted in a successful vaccination program launched by the World Health Organization. However, a large population is still unvaccinated, leading to the emergence of mutated strains like alpha, beta, delta
(abcA) gene, which is also a part of the ABC transporter family and could potentially play a role in multidrug antibiotic resistance; however, it is also an integral part of cell metabolism [64]. One CDSs was homologous to themrcAgene, which is responsible for the regulation of β-...
these functions may aid the animal in extracting nutrients from polysaccharides resulting from the degradation of plant and fungal biomass in the soil. In addition, several foreign genes are involved in antibiotic biosynthesis11,12. These genes are strongly induced by stress exposure13,14and it is ...
antibiotic biosynthesis, and sulfur metabolism. Although not directly related to host health but more to the environment as a whole, the presence of mercury resistance-related genes in the pBMC5 genome is of crucial interest. Heavy metals are known to be environmental toxins due to their bioaccumu...