TheApolipoprotein Elocus is a complex genomic region encoding APOE and the isoforms produced from its polymorphic alleles. APOE is involved in critical metabolic pathways, including lipid transport and metabolism46, and is associated with chronic diseases, including the development of atherosclerosis and ...
However, the lack of a fully annotated reference genome has hampered efforts to deconvolute its complex evolutionary history and functional gene dynamics. Here we present a high-quality reference genome of A. sativa and close relatives of its diploid (Avena longiglumis, AA, 2n = 14) and...
In order to make modern and generally very complex Monte Carlo generators compatible with the full JADE detector simulation, a utility for converting HepMC [114] events into JADE-readable format was created, thus avoiding the need of multiple different interfaces to MC event generators. 5.4 New ...
The Case of the Black Swan Season 37 Episode 32 Episode SummaryThe upcoming episode titled “The Case of the Black Swan” of “48 Hours” on CBS promises an intriguing investigation into a gripping crime story. This episode will explore a complex case that has captivated audiences with its ...
The complete solution for domain recognition. Supports screenshoting, port scan, HTTP check, data import from other tools, subdomain monitoring, alerts via Discord, Slack and Telegram, multiple API Keys for sources and much more. - atlassion/Findomain
Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dys
Atlas of tissue-specific retrotransposons. Figure S6. The complex evolution patterns of retrotransposons. Additional file 2: Supplementary Table 1. Species used in this study. Additional file 3: Supplemental Table S2. Retrotransposons identified in human. Additional file 4: Supplemental Table S3. ...
is the possibility of finding the requested resource in the cache. In most cases, LRU implementation is a good enough solution. JCS and ASP.NET caching is based on the LRU algorithm. In more complex scenarios, a combination of LRU and LFU algorithms such as the adaptive replacement cache (...
10e,h), as well as the circadian-rhythm-related genes SIX3/6a and PER1/2 (also expressed in the pineal complex; see the online atlas). Other neuropeptides expressed in the hypothalamus are galanin (GAL)54, somatostatins (SSTa and SSTc)55, NPY56, neurotensin (NTS), vasotocin (VAT), ...
Many cell types and essential regulatory factors related to regeneration have been uncovered based on the cell atlas11,12,13. However, for determining the spatial distribution of gene expression during the regenerative process, previous studies mainly employed the in situ hybridization based staining ...