The second obstacle to establishing accurate information on causes of AKI and therefore on risk assessment is that we continue to have an incomplete understanding of the pathogenesis of AKI in many of the circumstances in which it is seen. Although there are many reasons for this, we and others...
Although data are currently sparse, it is likely that if one were to combine in one category all unilateral and bilateral visual loss due to infectious causes of keratitis [24], optic neuritis [25], uveitis [26] and orbital cellulitis [27], infectious disease would feature more prominently a...
Island faunas can be characterized by gigantism in small animals and dwarfism in large animals, but the extent to which this so-called ‘island rule’ provides a general explanation for evolutionary trajectories on islands remains contentious. Here we us
Increasing Incidence, Cost, and Mortality of AKI and HRS in Hospitalized Patients With Cirrhosis Daniela Goyes, MD; Basile Njei, MD, MPH, PhD; Joseph K. Lim, MD open access JAMA Netw Open Abstract Full Text pdf link PDF RESEARCH LETTER SUBSTANCE USE AND ADDICTION MAY 21, 2025 ...
Why have a definition of acute kidney injury? Acute kidney injury (AKI) is a frequent and sometimes devastating syndrome, with high costs to patients and health-care systems.1,2 It has multiple risk factors or causes.2,3 A uniform definition of AKI is needed that can be applied in both ...
This combinatorial therapy may represent a new therapeutic option for the treatment of AKI and should be further investigated in the future.Background The two most common causes of acute kidney injury (AKI) are ischaemia/reperfusion (I/R) injury and nephrotoxic agent exposure [1]. Cisplatin is...
The activation of the unfolded protein response (UPR) is closely linked to the pathogenesis of renal injuries. However, the role of XBP1, a crucial regulator of adaptive UPR, remains unclear during the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). Methods We charac...
Common causes of client errors There are a number of reasons that you might encounter an error while performing a request. Some errors can be prevented or easily solved by following these guidelines: Specify the Region: Some resources can't be shared between AWS Regions. If you are specifying...
Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-thre
Secondary hyperparathyroidism is a disorder characterized by increased serum PTH levels due to parathyroid gland hyperplasia, triggered by hypocalcemia, hyperphosphatemia, or decreased serum vitamin D concentration. The most common causes of sHPT are vitamin D deficiency and chronic renal disease. Sometimes...