Duration of action depends on measured parameters. Intestinal absorption of THC is increased by application in a lipophilic base. Cannabinoids are present in the plant mainly as pharmacologically inactive carboxylic acids (more than 95%), that are transformed into the active phenols by heating...
The duration that weed stays in the body varies greatly among individuals based on factors like the frequency of use, body fat, metabolism, and the potency of the cannabis consumed. Typically, THC can be detected in urine for up to 30 days after use in regular users, less in occasional us...
The medicinal plantCannabis sativa L. (C. sativa)is currently being extensively studied to determine the full extent of its therapeutic pharmacological potential. Δ9-tetrahydocannabinol (THC) and cannabidiol (CBD) are the most thoroughly investigated compounds. We aimed to explore the anticancer acti...
To determine whether THC was manipulated from injection to injection by varying the exposure alters baseline levels of locomotor activity, two 30- duration of syringe-pump activation (approximately 0.5– min locomotor sessions were conducted: the first was 1 day 2 s). Three different doses of ...
The increased legal availability of cannabis has led to a common misconception that it is a safe natural remedy for, among others, pregnancy-related ailments such as morning sickness. Emerging clinical evidence, however, indicates that prenatal cannabis
Video-EEG and polygraphic recordings, imaging studies, laboratory testing, and seizure frequency, type, and duration, and adverse effects. As the primary outcome, a reduction of frequency of epileptic spasms (ES) was assessed. ES freedom was considered after a minimal time of 1 month without ES...
The effects of the cited doses of cannabinoids were also examined on spontaneous locomotor activity and rearing frequency for a 20-min duration 10 min after cannabinoid injection. The tested cannabinoids reduced the frequencies of HTR and ESR in SR 141716A-injected mice. These agents also ...
Fig. 1. Yield of hemp seed oil after different pretreatment (a). Effects of power and time of ultrasonic pretreatment on hemp seed oil (b) and (c). Fig. 1c shows the influence of ultrasonic treatment duration on oil yield and the degradation rate of Δ9-THC. The oil yield exhibited ...
Standard click trains were 500 ms in duration and 80 dB SPL (C weighting). Neuropsychopharmacology In each task block, subjects were asked to press a response key to the target stimuli with the index finger of their preferred hand. Each block comprised 15 targets, 15 distractor stimuli, and...
Target tones and standard click trains were 500 ms in duration, whereas distractor stimuli ranged in duration from 175 to 250 ms. All stimuli were presented binaurally using at an intensity of 80 dB SPL. GABA cannabinoid interactions and psychosis R Radhakrishnan et al Table 1 Schedule of Test...