THC is a highly fat-soluble substance, which means that it may stay longer in lipid-rich tissues such as the lungs, heart, brain, and liver [72]. Studies suggest that brain levels of THC are almost always higher than blood levels, and there may be THC in the brain even when it is ...
such as THC seltzers, andCBD gummies. While both provide the therapeutic properties of cannabis, they differ in their onset of effects, duration, and user preferences. Let’s delve into the distinctions between THC beverages and CBD
An addiction to marijuana has fewer health risks than many other drugs. Cannabis offers health benefits, so using it responsibly will not deteriorate your physical condition. A proper balance of THC and CBD can reduce stress, improve mood and heal brain injury. The impact THC has on the pleasu...
Ligands acting on cannabinoid receptor 1 (CB1R) are also potential targets for the treatment of other health conditions. Using an evidence-based approach, pharmacological investigation of CB1R agonists is timely, with the aim to provide chronically ill patients relief using well-defined and ...
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In this context, CBD use may afford individuals the ability to engage in daily activities and workplace duties which they may otherwise be unable to do. Hence, efforts to clarify the risk of CBD-associated impairment are greatly needed to inform public health legislation, as well as workplace...
This manuscript in-depth review will investigate the potential of the ECS in the treatment of various diseases, and to put forth the suggestion that many of these secondary metabolites ofCannabis sativaL. (hereafter referred to as “C. sativaL.” or “medical cannabis”), may also have potent...
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All animal procedures were approved by the Institutional Animal Care and Use Committee (IACUC; covered by Animal welfare assurance No A3011-0), SUNY Stony Brook, School of Medicine and conducted in accordance with National Institutes of Health “Guide for the Care and Use of Laboratory Animals”...
Additionally, it was able to slow fibrosis progression and to attenuate established fibrosis. Thus, dual-target peripheral CB1R/iNOS antagonists have therapeutic potential in liver fibrosis. Regarding the pharmacodynamics of the hybrid CB1R/iNOS inhibitor, two important principles have emerged from effort...