The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mous...
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mous...
对小鼠的研究表明,这种蛋白可能调节间充质细胞的细胞表面特性,并参与细胞粘附和迁移。 The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to fun...
THBS2在与RFS和OS负相关的module(pink和black module)中都是排在前列的hub gene;同时THBS2能通过外泌体分泌,调控细胞-细胞和细胞-基质相互作用,可能对肿瘤微环境有潜在影响;THBS2在肺腺癌病人的外周血中可以被检测到,这意味着它有成为肺...
Gene ontology and pathway enrichment analysis were performed by the enrichr database. Protein interaction analysis was performed by STRING online database. Validation of expression and coexpression analyses was performed using a qRT-PCR experiment. Results. Based on bioinformatics analyse...
(Differentialgeneanalysis),筛选标准为差异倍数(Foldchange,FC) ≥2且FDR(Falsediscoveryrate,对差异显著性P值(p-value)进行校 正所得)0.01;随后按照“功能注释”可筛选到与血管生成相关的差异 表达基因(Differentiallyexpressedgenes,DEGs)THBS2。 2)血管生成相关DEGs的GO功能和KEGG信号通路富集分析 将血管生成相关差异...
该THBS2 Polyclonal Antibody. The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angi...
THBS gene family is generally upregulated and significantly associated with disease progression in pan-cancer. (A-B) The number of TCGA and GTEx samples applied in this study, respectively. (C) The mRNA expression differences between normal and tumor samples. (D-F) The mRNA expression difference...
Figure . Gene Sequencing (extract) Figure. SDS-PAGE [ IMPORTANT NOTE ] The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures. 特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非...
Interestingly, combination the average of top 20 genes and THBS2 showed a higher risk in overall survival (p < 0.001, 2.890(1.676–4.981)) than the average of top 20 gene without THBS2. The results indicated that THBS2 increased HR value, which might be considered as a ...