In addition to cytokine production profiles, there are a number of cell surface markers proposed to differentiate Th1 vs. Th2 subtypes. For example, Th1 cells express both components of IL-12 receptor chains (beta 1 and alpha.32,33 Only Th2 cells appear to express a fully functional IL-1...
Polarized expression of Th1 and Th2 markers on infiltrated lymphocytes in gastric mucosa of Helicobacter pylori-induced gastritisHelicobacter heilmanniiacute gastric mocosal lesionstouch cytologyA 69-year-old-woman presented with acute epigastric pain, nausea, vomiting and heartburn. Endoscopy disclosed ...
Methods: In this study, we evaluated pre-challenged immune responses related to the Th1 (IFN-gamma and IL-12) and Th2 (IL-4 and IL-10) cytokine profiles, and the CD4, CD8, CD3, and CD25 markers of T cells. This measurement was followed by vaccination accompanied by two one-week ...
nature publishing group ARTICLES Intranasal bacteria induce Th1 but not Treg or Th2 M Costalonga1, PP Cleary2, LA Fischer1 and Z Zhao1 Commensal microorganisms colonize the nasal mucosa without inducing inflammation. Pathogens perturbing the commensal flora often invade evading immune defenses. The ...
Thus, the purpose of the present study was to further investigate the phenotype of T lymphocytes in BALF and in induced sputum in patients with pulmonary sarcoidosis with focus on expression of markers indicating Th1 and Th2 cellular function. Our findings suggest a shift toward a type-1 ...
levels of serum tumor markers such as carcinoembryonic antigen (CEA) and carbohy-drate antigen 15-3 (CA15-3), and levels of helper T cells Th1 / Th2 cytokines like interleukin-6 (IL-2), interferon-γ (IFN-γ), IL-6 before and after treatments, as well as toxic side effects between...
Nicotine, a definite risk factor during pregnancy, is an immunomodulator. This study was designed to investigate the effects of prenatal nicotine exposure (PNE) on the balance of Th1/Th2 in offspring, and further explore the developmental origin mechanis
To investigate the pattern of Th1/Th2 immunity in the airways of asthmatics upon viral infections, the type 2- ( IL-4 and IL-5) and type 1-( IFN-γ) inflammatory markers were measured in induced sputum from the individuals. Initially, compared to the healthy controls, the two asthma ...
In general, control staining levels were established by setting quadrant markers with > 98% negative staining. When more than one sample from an individual was stained for the same cytokine, sample values were averaged for that individual. Antibodies The antibodies used in this analysis were IL...
In the concomitant presence of IL-13 and IFN-g, there were increases in (a) DUOX2 mRNA and (b) DUOX2 protein over that of either IFN-g or IL-13 alone. P-value for interaction is o0.001 for both markers, *Po0.025, **Po0.001; n ¼ 16 for DUOX2 mRNA, n ¼ 11 for DUO...