正如一些科学家最近指出的那样,整个 Th1/Th2 理论的主要问题是细胞因子和其他免疫信使的活性很少落入严格的 Th1 或 Th2 模式。一些细胞,如非辅助调节性 T 细胞 ( Tregs ),可能会影响 Th1 和 Th2 反应 [ 1 , 2 , 3 ]。 新研究 所谓的Th17 细胞最近才被发现,科学家认为它们可以填补缺失的空白并解释与 ...
T helper (TH) 1 cells secrete interferon (IFN)-γ and interleukin (IL)-2 but not IL-4, whereas TH2 cells secrete IL-4 and -5 but not IFN-γ. The type of T helper cell subsets involved in atopic eczema (AE) and the signals provided by them in vivo are still subject to debate ...
Very low and very high antigen doses have been suggested to promote a Th2 response, while moderate antigen levels predispose naive cells to become Th1 cells.45 Alternatively, when dose and affinity of antigen are considered concurrently, exact opposite results are reported. Low and high doses ...
Díaz;M;A;Villalobos;N;de;Aluja;A;Rosas;G;Goméz-Conde;E;Hernández;P;Larralde;C;Sciutto;E;Fragoso;G.Th1and Th2 indices of the immune response in pigs vaccinatedagainst Taenia solium cysticercosis suggest various hostimmune strategies against the parasite.Veterinary Immunologyand Immunopathology.2003...
本人用ELISA方法检测良恶性胸腔积液中Th1型细胞代表因子IFN-γ和Th2型细胞代表因子IL-4的水平,观察患者的Th1/Th2免疫反应状态,将有助于揭示晚期肺癌病人的免疫调节机制。 1材料与方法 1.1.1恶性胸腔积液组:共30例(男21,女9) ,平均年龄59. 3岁。均经支气管镜检查、淋巴结活检、胸膜活检、肿块穿刺、胸腔积液...
All allergic subjects tested (16/16) produced high levels of interferon-gamma (IFN-γ) in response to Cry j 1 with a mean value of 918 pg/ml, while only five subjects showed significant elevation of IFN-γ production in response to Cry j 2 with a mean value of 679 pg/ml. The ...
Genes and Immunity is a journal dedicated to functional genetics of the immune response. Emphasizing studies that demonstrate genetic, genomic or functional variation in the immune system, Genes and Immunity assists our understanding of how the basic control over the immune system varies between indivi...
Th 细胞的分化与 DC 细胞的关系 热度: DC的分化和Th1、Th2细胞的诱导 阴晴1,邵启祥2,王金湖3 (1.江苏大学附属医院检验科,江苏镇江212001;2.江苏大学医学技术学院免疫学教研室,江苏镇江212001;3.太仓市人民医院检验科,江苏太仓,215400) [关键词]DC;Th细胞;诱导分化 ...
占优势成正相关,Th2活性优于Th1活性可能促使SLE患者自身抗 体的产生. 关键词:系统性红斑狼疮;Thl/Th2细胞因子;类风湿因子;抗心磷脂抗 体 中图分类号:R593.241文献标识码:A文章编 号:1672—0709(2005)03—0141—03 CorrelationBetweenThl/Th2lmbaIanceandRheumatoidFactorsandAntica ...
However, rather than conforming to stringent TH1 or TH2 subtypes, single-cell analysis reveals that the predominant response is a highly mixed TH1/TH2 function in the same cell. The regulatory T cell activity, although observed in a small fraction of activated cells, emerges from this hybrid ...