Type 1 T helper (Th1) cells represent one of the different subsets of the heterogeneous Th CD4+ population. These cells are characterized by the production of interferon (IFN)-纬 as signature cytokine, but they can also produce interleukin (IL)-2 and lymphotoxin-伪. Th1 cells originate from...
【1】Basu A, Ramamoorthi G, Albert G, et al. Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy. Front Immunol 【2】Zhu J. T Helper Cell Differentiation, Heterogeneity, and Plasticity. Cold Spring Harb ...
中文名称:TH1 Cells(赠送Str鉴定报告)|小鼠调节T细胞 英文名称:TH1 Cells 保存条件: 常温培养或液氮冻存 纯度规格: TH1 Cells(赠送Str鉴定报告)|小鼠调节T细胞 产品类别: 生物试剂 "TH1 Cells(赠送Str鉴定报告)|小鼠调节T细胞 细胞背景资料:调节T细胞 细胞形态:上皮细胞样 接收细胞相关问题:如不能在收到细胞后及时...
保存条件:液氮保存纯度规格:1x10(6)viable cells/ml 产品类别:实验化学品 "TH1 Cell:小鼠调节T细胞系 细胞形态:上皮细胞样 细胞生长:贴壁 细胞背景资料:调节T细胞 Leydig细胞系相关产品:CTSC-3细胞、BPH-1细胞、MC3T3-L1细胞 L M (TK-)细胞系相关产品:UT-7细胞、FRTL-5细胞、58F细胞 ...
Luckheeram RV, Zhou R, Verma AD et al.(2012) CD4+T cells: Differentiation and functions.Clin Dev Immunol 2012:925135. Raphael I, Joern RR, Forsthuber TG (2020) Memory CD4+ T cells in immunity and autoimmune diseases.Cel...
Classical dendritic (cDC) cell stimulation of CD4+ T cells and CD8+ T cells. 就像一个足球队的教练收集对手信息、拟定作战计划一样,树突状细胞作为免疫系统球队的“教练”,也同样要收集关于入侵的信息,并决定免疫系统要怎样地产生反应。这就是树突状细...
近年来,在对小鼠实验和人体免疫的研究中发现,疫苗的保护效果和患者的预后及转归情况与多功能性T细胞(polyfunctional T cells)的数量和质量密切相关。以往仅仅检测某种或少数几种效应T细胞的功能,远远不能代表机体的特异性免疫状态。在单个细胞水平上,同时产生两种或以上效应功能,包括细胞因子、趋化因子及杀伤功能的细胞被...
IL 21可诱导所有B细胞亚群(包括新生B细胞、初始B细胞、过渡型B细胞、生发中心B细胞以及记忆B细胞)分化为Ig分泌细胞(Ig secreting cells, ISC),分泌大量IgM、IgG和IgA[14, 20-22]。一般来说, IL 4对初始B细胞的作用要明显强于作用于GC和记忆B细胞的作用;而IL 10则优先增强GC中的B细胞和记忆B细胞分化为ISC...
2022年9月15日,清华大学董晨及美国德克萨斯大学安德森肿瘤中心Seon Hee Chang共同通讯在Journal of Clinical Investigation(IF=19)在线发表题为“The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity”的研究论文,该研究表明FoxO4/DKK3轴抑制Th1细胞的IFN- γ表达并限制抗微...
Although IL-10 was originally isolated from T(H)2 cells it is now known to be produced by many cell types. Here, we discuss the recent evidence that shows that T(H)1 cells are the main source of IL-10 that controls the immune response against Leishmania major and Toxoplasma gondii ...