differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016...
此外,TGFB1基因还促进上皮间质转化 (EMT),从而促进癌细胞的转移。 该研究发表在《Nature》子刊上,原文题目为“Assessment of the TGFB1 gene expression and methylation status of the promoter region in patients with colorectal cancer...
Gene ID: 7040 种属 Homo sapiens 基因序列编号: NM_000660.7 基因描述 Homo sapiens transforming growth factor beta 1 (TGFB1), mRNA DNA编码区: atgccgccctccgggctgcggctgctgccgctgctgctaccgctgctgtggctactggtg ctgacgcctggccggccggccgcgggactatccacctgcaagactatcgacatggagctg gtgaagcggaagcgcatcgaggccatccgcggcc...
这种基因在肿瘤细胞中经常上调,这种基因的突变会导致化脓性恩格曼病。 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription f...
TGFB1 gene polymorphisms: their relevance in the susceptibility to Helicobacter pylori -related diseases. Genes Immun 2006;7:640–646.Garcia-Gonzalez M. A., Strunk M., Piazuelo E., Benito R., Santolaria S., Jiménez P., et al. . (2006). TGFB1 gene polymorphisms: their relevance in ...
基因简称(symbol) TGFB1 [HGNC] [GeneCards] [NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) CED|TGFbeta 基因家族代码(gene_family_id) 542 [HGNC] [GenScript] omim代码 190180 entrez码 7040 [Vega] ensembl基因码 ENSG00000105329 [Ensembl] 基因家族(gene family) ...
提供的TGFB1人源重组蛋白(Q02)产品为带有GST标签的人源TGFB1部分序列重组蛋白,其对应的GeneID号为7040。 产品描述 与其它公司提供的重组蛋白不同,该TGFB1人源重组蛋白(Q02)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译...
Figure . Gene Sequencing (extract) Figure. SDS-PAGE [ IMPORTANT NOTE ] The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures. 关键字:TGF-B1;CED;DPD1;转化生长因子β1(TGFb1)重组蛋白; ...
Gene Info — TGFB1 Interactomes Pathways Diseases Related Products P10414 LRRC32/TGFB1 (Human) Recombinant Protein (Biotin) P10451 TGFB1 (Human) Recombinant Protein (Biotin) P10028 LRRC32/TGFB1 (Human) Recombinant Protein P9807 LRRC32/TGFB1 (Human) Recombinant Protein P9808 LRRC...
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and ne...