(2000) A mechanism of suppression of TGF-b/SMAD signaling by NF-kB/RelA. Genes Dev. 14, 187-197Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, BoEttinger EP. 2000. A mechanism of sup
借助JAKs激活STAT,而影响到基因调节的通路为( )A.细胞因子信号转导通路B.NF- kB信号通路C.MAPK信号D.TGF- B信号通路E. Wnt信号通路
and activates IKBKB and MAPK8 in response to TRAF6 signalling. It also stimulates NFKB activation and activation of the p38 MAPK pathway. It is responsible for controlling a variety of cell functions such as transcription and apoptosis. TAK1 is important for TGF-B1 regulation of MMP9 and the...
AP-1 and NF-KB.3,10–12 TGF-b signaling towards growth inhibition is mediated by Smad complexes with FoxO factors, which activate the cell cycle inhibitors p15INK4b and p21CIP1,13,14 and with E2F4/5 and ATF3 factors, which inactivate c-Myc and ID1, respectively.15–17 In addition, ...
Together, these results indicate that an increased NF-κB activation upon TGF-β treatment is responsible for the resistance to the cytokine in PTP1B-deficient hepatocytes. Download: Download high-res image (834KB) Download: Download full-size image FIGURE 4. PTP1B−/− hepatocytes show an...
NF-kB 1162022-12 2 TGF B--Smad信号通路 812022-12 3 PI3K-PKB信号通路 902022-12 4 Jak-STAT信号通路 892022-12 5 Ras-MAPK磷酸化级联反应及基本步骤 702022-12 6 Ras蛋白的活化 682022-12 7 Ras蛋白及功能、Ras突变、Sos蛋白 712022-12 8 受体酪氨酸激酶的激活机理 742022-12 9 受体酪氨酸激酶与细胞...
1.芪杞益肾胶囊对糖尿病肾病模型大鼠肾脏组织中 TGF-β1 表达的影响 [J], 钱雅 玉;张轶欧 2.积芎解毒方延缓糖尿病肾病发展及影响炎症因子水平的研究 [J], 王峥;张翥 3.积芎解毒方对糖尿病肾病大鼠肾组织 NF-KB、AngⅡ表达的影响 [J], 王峥; 李 建鹏; 张翥; 彭贵军 4.积芎解毒方对糖尿病肾病大鼠肾...
TGF-B promotes EMT and metastasis of pancreatic cancer cells through Src and NF-kB pathway-dependent repression of PP2Acdoi:10.1016/j.pan.2017.07.036Wu, JingLi, WeiPancreatology
Involvement of NF-kB in TGF-b-mediated suppression of IL-4 signalingYamamotoT.ImotoS.SekineY.SugiyamaK.AkimotoMuraguchiingentaconnectBiochemical & Biophysical Research Communications
Benazepril inhibited the NF-kappaB and TGF-beta networking on LV hypertrophy in rats [ J ]. Immunol Lett, 2013, 152 (2) : 126-134.Yan SH;Zhao NW;Zhu XX;.Benazepfil inhibited the NF-KB and TGF-13networking on LV hypertrophy in rats.Immunol Lett.2013.126-134...