2000. A mechanism of suppression of TGF- b/SMAD signaling by NF-kB/RelA. Genes Dev. 14: 187-197.Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, et al. A mechanism of suppression of TGF-b/Smad signaling by NF-kB/RelA. Genes Dev 2000;14:187-98....
It also stimulates NFKB activation and activation of the p38 MAPK pathway. It is responsible for controlling a variety of cell functions such as transcription and apoptosis. TAK1 is important for TGF-B1 regulation of MMP9 and the metastatic potential of certain breast cancer cell lines....
对BLM大鼠肺组织中NF-kBmRNA的表达及ICAM-1、TGF-βB.的表达进行了定量研究.结果:抗肺纤胶囊能明显抑制BLM大鼠肺组织中NF-kBmRNA、ICAM-1、TGF-β1的高表达(P<0.05,0.01),并呈现出一定的剂量依赖关系.结论:具有补益肺肾、活血通络作用的抗肺纤胶囊可阻断肺泡炎继续发展的中心环节-NF-kB的活化,抑制ICAM-1...
The effects observed with our studies suggest that CSE-induced activation of ERK1/2 and NF-kB sign...Lu S,Dong Z.Y.Characterization of TGF-β-regulated interleukin- 8 expression in human prostate cancer cells. Prostate The . 2006Lu S, Dong Z. Characterization of TGF-beta-regul...
AIM:To investigate the effect of pyrrolidine dithiocarbamate(PDTC),a novel nuclear factor-_KB (NF-_KB) inhibitor,onexpression of multiple inflammatory medi... Xiao-Ping,Gu,Fu-Tao,... - 《World Journal of Gastroenterology》 被引量: 4发表: 2004年 TGF-β1基因修饰的脾细胞对大鼠肝脏移植免疫耐...
NF-KB,α-SMA及TGFβ1在实验性肝损伤中的表达 (TGF) β1在实验性肝损伤大鼠不同时期的免疫组化表达及其定位情况,探讨其在肝损伤过程中的变化规律及相互关系.方法 采用四氯化碳( CCl4)复合因素诱发大鼠肝纤维化... 李亚萍,党双锁,翟嵩,... - 《临床肝胆病杂志》 被引量: 0发表: 2011年 ...
Enterococcus faecalis monoassociated wild type and IL-10 gene deficient mice differentially induce NF-KB and TGF-B/SMAD signalling intestinal epithelial cells 来自 ResearchGate 喜欢 0 阅读量: 13 作者:A Shkoda,SC Kim,RB Sartor,D Haller 摘要: Nonpathogenic enteric bacterial species initiate and ...
黄芪对实验性IgA肾病大鼠肾小管问质损害及NF-κB MCP-1表达的影响 目的 观察黄芪对实验性IgA肾病大鼠肾间质损害及肾组织核转录因子-KB(NF-kB)、单核细胞趋化蛋白(MCP-1)表达的影响,探讨黄芪防治IgA肾病肾小管问质损害的作用机制.方法 ... 张国珍,吴小川,彭晓杰,... - 《中国当代儿科杂志》 被引量: 0发...
NF-kB 1032022-12 2 TGF B--Smad信号通路 702022-12 3 PI3K-PKB信号通路 782022-12 4 Jak-STAT信号通路 802022-12 5 Ras-MAPK磷酸化级联反应及基本步骤 622022-12 6 Ras蛋白的活化 592022-12 7 Ras蛋白及功能、Ras突变、Sos蛋白 632022-12 8 受体酪氨酸激酶的激活机理 692022-12 9 受体酪氨酸激酶与细胞...
(TNF) were among the most likely upstream regulators of DEGs in both #BiAll-93 and #MonoAll-2.13 cells (Supplementary Table 8). TGFB1, TNF and their modulator and downstream effector nuclear factor kappa B (NFκB) were also central factors in the causal networks of functions, and in ...