关键词:TGFβ1/Smad;信号通路;肾间质纤维化;中药单方;复方中药 中图分类号:R284.2文献标志码:A文章编号:1674-8999(2014)06-0780-03 RegulationofTraditionalChineseMedicineTGF-beta1/SmadSignalingPathways InterventionMechanismofRenalInterstitialFibrosis ZhangLinqi 1 ,WangQing 1 ,WangZetian 2 1.TheFirstAffiliated...
英文名称: TGF-beta/Smad Compound Library 总访问: 61 国产/进口: 进口 半年访问: 2 产地/品牌: Medchemexpress (MCE) 产品类别: 生化试剂 规格: 最后更新: 2024-11-4 货号: HY-L018 CAS 号: 参考报价: 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:微信新浪...
Inflammatory bowel diseases (IBDs) are caused by an aberrant and excessive local immune response to components of the bacterial microflora that are: poorly controlled by endogenous counter regulatory mechanisms such as the immunosuppressive cytokine transforming growth factor-beta1 (TGF-beta1). Studies ...
Collectively, these results indicate that Nrf2 might be an effective inhibitor of Smad-dependent Tgf-beta1 signaling, and imply the anti-fibrotic role of Nrf2 in renal diseases. 展开 关键词: Renal fibrosis Nrf2 Smad7 DOI: 10.1254/jpssuppl.WCP2018.0_PO1-3-20 ...
1.Willems E, et al. Cell Stem Cell. 2012 Aug 3;11(2):242-252. 关键词 Transforming growth factor beta receptorsTGF-β/SmadTGF-β ReceptorTGFβTGFbeta/SmadTGF-betaTGFbetaTGF-b/SmadTGFbSmadITD-1ITD1ITD 1InhibitorinhibitRelated Tags: buy ITD-1 | purchase ITD-1 | ITD-1 cost | order ...
TGF-beta-induced EMT was blocked by RNA silencing of HEY1 or JAG1, and by chemical inactivation of Notch. The EMT phenotype, biphasic activation of Hey1, and delayed expression of Jag1 were induced by TGF-beta in wild-type, but not in Smad3-deficient, primary mouse kidney tubular ...
OBJECTIVE: To investigate the influence of exogenous transforming growth factor beta 1 (TGFbeta1) on growth and signal inhibitor Smad7 protein and its mRNA in BRL cells (rat liver cell line). METHODS: BRL cells were incubated with TGFbeta1 and divided into 0 minute group, 90 minute group ...
Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-beta 1/Smad3 pathway (vol 39, pg 153, 2017) Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-β1/Smad3 pathway. Int. J. Mol. Med....
A family of structurally related proteins homologous to the Drosophila mothers against dpp (MAD) gene product have been implicated in signal transduction by members of the TGF-beta superfamily. One of these MAD related proteins (DPC4) has been cloned as a candidate tumour suppressor in pancreas ...
Galectin-1 expression in activated pancreatic satellite cells promotes fibrosis in chronic pancreatitis/pancreatic cancer via the TGF-β1/Smad pathway et al: Galectin‑1 expression in activated pancreatic satellite cells promotes fibrosis in chronic pancreatitis/pancreatic cancer via the TGF‑β1/......