The present invention relates to the use of the antibodies against human transforming growth factor β receptor II (TGFβRII) antibodies, pharmaceutical compositions comprising the antibody either alone or in combination, for example, for the treatment of cancer and fibrosis.吴嫣...
Expression of TGF-betas and TGF-beta type II receptor in cerebrospi- nal fluid of patients with idiopathic normal pressure hydrocephalus. Neurosci Lett. 2007; 413(2):141-4. doi: 10.1016/j.neulet.2006.11.039 PMID: 17194537Li X; Miyajima M; Jiang C;.Expression of TGF-betas and TGF-beta...
除了直接诱导或抑制靶基因表达外,TGF-βα还诱导多种复杂的细胞反应,具体取决于细胞类型,其中最显著的是涉及PI3K(Phosphatidylinositol-3-Kinase)和PP2A(Protein Phosphatase-2A)的G1晚期的生长停滞、分化程序的变化和凋亡(参考文献3)。其他生长因子也可以通过Ras的GRB2(Growth Factor Receptor-Bound Protein-2)-SOS激活...
TGF-BETA-RECEPTOR TYPE II GENEPURPOSE: To obtain the subject gene coding a transforming growth factor-β (TGF-β) receptor type II having a specific amino acid sequence, and giving a TGF-β receptor protein useful for the therapy of cancer, etc.OKAI HIDEO...
英文名字 Anti-TGF beta Receptor II antibody供应商 MyBioSource产品货号 MBS176195产品报价 ￥询价/0.1mg ￥询价/5x0.1mg ￥询价/其它规格产品说明书 点击查看购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868产品新闻...
Mutational analysis of TGF-beta type II receptor, Smad2, Smad3, Smad4, Smad6 andSmad7 genes in colorectal cancer. J Exp Clin Cancer Res 2003;22:315-320Fukushima T, Mashiko M, Takita K, et al. Mutational analysis of TGF-β ... T Fukushima,M Mashiko,K Takita,... - 《Journal of ...
Rabbit TGF beta Receptor II (Ab-250) Antibody 供应商 MyBioSource 产品货号 MBS004195 产品报价 ￥询价/0.1mL ￥询价/0.2mL ￥询价/其它规格 产品说明书 点击查看 购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...
TGF beta 2重组蛋白;高活性/TGF beta 2 protein价格:￥710/支产品详情:中文名称:(TGFβR2)重组蛋白 英文名称:Recombinant Transforming Growth Factor Beta Receptor II (TGFbR2) 英文简... 纯度:95% 包装规格:10ug/50ug/100ug/1mg 用途:仅供科研使用 ...
简短描述:Recombinant; Rabbit anti Human TGF beta Receptor II Antibody; WB; Unconjugated 种属反应性:人(Human) 亚型:Rabbit IgG 应用: WB 货号(SKU)包装规格是否现货价格数量 Ab130884-10μl 10μl现货 原价:¥499.90 +- Ab130884-50μl 50μL现货 ...
(transforming growth factor beta receptor 2) 该基因编码的蛋白是一种跨膜蛋白,具有蛋白激酶结构域,与1型转化生长因子β受体形成异二聚体复合物,并与转化生长因子β结合。这种受体/配体复合物磷酸化蛋白质,然后进入细胞核,调节与细胞增殖、细胞周期阻滞、伤口愈合、免疫抑制和肿瘤发生有关的基因转录。该基因突变与...