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The precise interactions through which it performs this function are not clear but here LTBP-2 is drawn as serving a speculative bridging role for illustrative purposes. In an attempt to answer the question whether LTBP-4 binding to TGFβ plays an important role in regulating TGFβ1 availability...
Invariant natural killer T cells: bridging innate and adaptive immunity Cells of the innate immune system interact with pathogens via conserved pattern-recognition receptors, whereas cells of the adaptive immune system recogniz... LV Kaer,PL Wu - 《Cell & Tissue Research》 被引量: 186发表: 2011...
Pereira, Editorial: Coarse graining in quantum gravity — Bridging the gap between microscopic models and spacetime physics, arXiv:2103.14605 [INSPIRE]. A. Eichhorn and T. Koslowski, Continuum limit in matrix models for quantum gravity from the Functional Renormalization Group, Phys. Rev. D 88 (...
Li Y et al (2013) USP2a positively regulates TCR-induced NF-kappaB activation by bridging MALT1-TRAF6. Protein Cell 4(1):62–70 Article CAS PubMed Google Scholar He X et al (2013) USP2a negatively regulates IL-1beta- and virus-induced NF-kappaB activation by deubiquitinating TRAF6. J...
Bridging the gap: understanding embryonic intervertebral disc development. Cell Dev Biol 2012; 1: pii: 103. 12 Ellis K, Hoffman BD, Bagnat M. The vacuole within: how cellular organization dictates notochord function. Bioarchitecture 2013; 3: 64–68. 13 Choi KS, Harfe BD. Hedgehog signaling ...
Bridging the BMP and Wnt pathways by PI3 kinase/Akt and 14-3-3zeta. Cell Cycle 2005; 4:215–216. CAS PubMed Google Scholar Waite KA, Eng C . BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels. Hum Mol Genet 2003; 12:679–684. CAS PubMed Google ...
SMAD2/3 phosphorylation is dependent on the SMAD anchor for receptor activation (SARA), which is a bridging factor with binding sites for the TGF-β-receptor, SMAD2 and early endosomes, and is associated with TGF-β signal activation [18], [19], [20]. A third SMAD protein, the ...
Bridging peripheral nerve defects with a tissue engineered nerve graft composed of an invitro cultured nerve equivalent and a silk fibroin-based scaffold -... Tissue engineered nerve grafts are considered as a promising alternative to autologous nerve grafts used for peripheral nerve repair. The diffe...
Administration of human FOLR3 to mice induced severe bridging fibrosis and an ECM pattern resembling human MASH. Our study thus uncovers a role of FOLR3 in enhancing fibrosis. Editor's summary: Metabolic dysfunction–associated steatohepatitis (MASH) fibrosis can be deadly bu...