TGF-beta activation of Smad3 is mediated through TbetaRI. TGF-beta also activates PI3K/Akt/mTOR signaling pathway. TGF-beta increases PI3K activity by &sim2.3- and 2.5-fold in the 10A and 10AT cells, with no TGF-beta response in the CA1h and CA1a cells. TGF-beta increases Akt ...
Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. Am J Physiol Renal Physiol 2009; 297: F1316-F1323.Hubchak SC,Sparks EE,Tomoko Hayashida, et al.Rac1 promotes TGF-β-stimulated mesangial cell type I collagen expression through ...
内皮素激活PI3KAkt信号通路对恶性黑省略活性及TGFbeta1表达调,内皮素激活PI3KAkt信号通路对恶性黑省略活性及TGFbeta1表达调,核桃内皮的功效与作用,内皮细胞,血管内..
TNFalpha, PDGF, and TGFbeta syn- ergistically induce synovial lining hyperplasia via inducible PI3Kdelta. Mod Rheumatol 2015; 25: 72-78.Shibuya H1, Yoshitomi H, Murata K, et al. TNFα, PDGF, and TGFβ synergistically induce synovial lining hyperplasia via inducible PI3Kδ[ J]. Mod ...
TGF-beta1 induces COX-2 expression and PGE2 synthesis through MAPK and PI3K pathways in human mesangial cells. Kidney Int. 2006; 70: 901-909.Rodriguez-Barbero, A., Dorado, F., Velasco, S., Pandiella, A., Banas, B., and Lopez-Novoa, J. M. (2006). TGF-beta1 induces COX-2 ...
Involvement of PI3K/Akt pathway in TGF-beta2-mediated epithelial mesenchymal transition in human lens epithelial cells. Yao Ke,Ye Pan Pan,Tan Jian,Tang Xia Jing,Shen Tu Xing Chao. Ophthalmic Research . 2008Yao K,Ye PP,Tan J, et al.Involvement of PI3K/Akt Pathway in TGF-β2-Mediat...
PHP14 regulates hepatic stellate cells migration in liver fibrosis via mediating TGF-beta 1 signaling to PI3K gamma/AKT/Rac1 pathwayPHP14Hepatic stellate cellMigrationPI3K gamma/AKT/Rac1 pathwayLiver fibrosisHepatic fibrosis is characterized by the activatioJournal of molecular medicine: Official organ ...
Jeong HW, Kim IS (2004) TGF-beta1 enhances betaig-h3-mediated keratinocyte cell migration through the alpha3beta1 integrin and PI3K. J Cell Biochem 92:770–780Jeong HW, Kim IS (2004) TGF-beta1 enhances betaig-h3-mediated keratinocyte cell migration through the alpha3beta1 integrin and ...
SDF-1 Improves Renal Fibrosis in Type 2 Diabetes Mellitus Involving TGF-beta-mediated ECM via PI3K/AKT SignalingJ. XieJi ZhangH. Shuai
cPLA2|[alpha]| mediates TGF-|[beta]|-induced epithelial|[ndash]|mesenchymal transition in breast cancer through PI3k|[sol]|Akt signalingBrought to you by the editorial team of Cell Death and Differentiation, Cell Death and Disease is a peer-reviewed author-pays online journal in the field of...