Here, we show that the modest neuronal expression of a fusion protein of the biologically active MBP1 fragment and the enhanced green fluorescent protein (MBP1-EGFP) significantly improved the performance of spatial learning memory in Tg-5xFAD mice, a model of pathologic Aβ accumulation in ...
thebiologicallyactiveMBP1fragmentandtheenhancedgreenfluorescentprotein(MBP1-EGFP)significantlyimprovedtheperformanceofspatiallearningmemoryinTg-5xFADmice,amodelofpathologicAbaccumulationinbrain.ThelevelsofinsolubleAbandfibrillaramyloidweresignificantlyreducedinbigenicTg-5xFAD/Tg-MBP1-EGFPmice.Quantitative...
Here, we show that the modest neuronal expression of a fusion protein of the biologically active MBP1 fragment and the enhanced green fluorescent protein (MBP1-EGFP) significantly improved the performance of spatial learning memory in Tg-5xFAD mice, a model of pathologic Aβ accumulation in ...