产品名称:载药海藻酸钠纳米微粒; 载药PLGA纳米粒; TF-PEG-PLGA涂层的载药ZIF-8纳米粒 英文名称:Drug loaded sodium alginate nanoparticles; Drug loaded PLGA nanoparticles; TF-PEG-PLGA coated drug loaded ZIF-8 nanoparticles 描述:聚乳酸-羟基乙酸共聚物(poly(lactic-co-glycolic acid),PLGA)由两种单体——乳酸...
We further detected the levels of HIF-1伪, Bcl-2, Bax and Caspase-3 of K562 cells in transcription and protein under hypoxia regulated by DNR, DNR-PEG-PLL-PLGA and DNR-Tf-PEG-PLL-PLGA, respectively. DNR-Tf-PEG-PLL-PLGA had the best effect when compared with other groups. Furthermore...
11.将cooh-peg-plga活化后与转铁蛋白在pbs中混匀进行第二反应,后纯化溶于pbs,获得转铁蛋白修饰的peg-plga溶液,简称tf-peg-plga; 12.将所述载药zif-8纳米粒溶液和所述转铁蛋白修饰的peg-plga溶液混匀,获得覆盖tf-peg-plga涂层的载药zif-8纳米粒,简称zif-8/tf-peg-plga; 13.或者操作b: 14.将所述载药...
大包装聚已二醇衍生化磷脂酰乙醇胺(PEG-PE);DNR-PLGA-PLL-PEG-TF 西安齐岳生物科技有限公司可以自主生产合成各种纳米材料;聚合物;PEG衍生物;树枝状化合物;载药颗粒;产品纯化* 达98%+以上并可以提供液相图谱来佐证纯度,并且提供相关技术指导服务 齐岳生物*产品: DNR-PLGA-PLL-PEG-TF P(VCL-S-S-MAA)-PEG PLA...
本发明公开一种覆盖TFPEGPLGA涂层的载药ZIF8纳米粒及其制备方法与应用,所述包括:将目标药物,2甲基咪唑,硝酸锌加入甲醇溶液中混合进行第一反应,后纯化溶于甲醇,获得载药ZIF8纳米粒溶液;将COOHPEGPLGA活化后与转铁蛋白在PBS中混匀进行第二反应,后纯化溶于PBS,获得转铁蛋白修饰的PEGPLGA溶液;将所述载药ZIF8纳米粒...
Methods: The pharmacokinetics and tissue distribution of DNR/Tet-PLGA-PLL-PEG-NPs-Tf (D/T-PPP-NPs-Tf), DNR/Tet-PLGA-PLL-PEG-NPs (D/T-PPP-NPs) and DNR/Tet (Da) solution were compared following intravenous injection in the rats. Result: Compare to D/T solution, the parameters of DNR...