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Identification of broad neutralization epitopes in HIV-1 envelope spikes is paramount for HIV-1 vaccine development. A few broad neutralization epitopes identified so far are present on the surface of native HIV-1 envelope spikes whose recognition by ant
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The central DNA Flap is a determinant of HIV-1 nuclear import, however, neither cPPT nor CTS mutations entirely abolish nuclear import and infection. Therefore, to determine whether or not the DNA Flap is essential for HIV-1 nuclear import, we generated double mutant (DM) viruses, combining ...
The same does not hold true for other stem cells, such as hematopoietic stem cells, which display signs of cytotoxic damage after priming with DXR. We also showed that PTX-loaded MSCs are able to reduce tumor cell proliferation and endothelial cell viability in vitro and to reduce the growth...
A rolling hash algorithm produces a pseudo-random value based only on the current context of the input. The rolling hash works by maintaining a state based solely on the last few bytes from the input. Each byte is added to the state as it is processed and removed from the state after a...
A rolling hash algorithm produces a pseudo-random value based only on the current context of the input. The rolling hash works by maintaining a state based solely on the last few bytes from the input. Each byte is added to the state as it is processed and removed from the state after a...