TEX101 (testis-expressed 101), also known as SGRG (spermatogenesis-relat- ed gene protein), scleroderma-associated autoantigen, cell surface receptor NYD-SP8, CT131, PRO1884 or TES101RP, is a 249 amino acid protein that is thought to play a role in signal transduction. Functioning as a ...
Gene Symbol TEX101 Gene ID (NCBI) 83639 RRID AB_2878139 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is...
Fig. 1. Identification of rs35033974 variant in TEX101 gene. (A) Schematic representation of TEX101 gene and protein sequence, showing the missense variant c.296 G>T, and the amino acid substitution p.99 G>V. (B) TEX101 DNA sequencing of WT TEX101 patient (left panel), rs35033974 ...
biosynthesis does not likely occur in the adult testis. In the epididymal mature sperm, it is still unclear how ADAM3 is produced and where its production occurs. To address these questions, there may be limitations in using a gene disruption approach. Further studies will be required to elucid...
With four TEX101-regulated proteins (ADAM3–6) previously discovered in mice (7, 34), three correspond to pseudogenes in humans, whereas ADAM4 gene is not present in the human genome. Although human TEX101 is an outstanding biomarker of male infertility (28), its functional role in human ...