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(Cell-free assay) 11 nM13 nM In vitro In vitroIn HaCaT (3TP-luc) and 4T1 (3TP-luc) stable cells, 12b potently inhibits the TGF-β1-induced luciferase reporter activity with IC50 of 16.5 and 12.1 nM, respectively.[1]EW-7197 inhibits TGFβ-induced Smad2 or Smad3 phosphorylation and ...
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