Tetralogy of Fallot (TOF) (pronounced te-tral-uh-jee of Fal-oh), one of the most common congenital heart disorders, comprises right ventricular (RV) outflow tract obstruction (infundibular stenosis), ventricular septal defect (VSD), aorta dextroposition (overriding aorta), and RV hypertrophy ...
Tetralogy of Fallot (TOF) with absent pulmonary valve syndrome (APVS) occurs in 5% of patients with TOF. TOF-APVS includes an anterior malalignment ventricular septal defect (VSD) similar to TOF with pulmonary stenosis. The right ventricle is hypertrophied and may contain obstructing muscle bands...
Patients after surgical repair of Tetralogy of Fallot (rTOF) may suffer a decrease in left ventricular (LV) function. The aim of our study is to evaluate a novel method of assessing LV torsion in patients with rTOF, as an early indicator of systolic LV dysfunction. Motion tracking based on...
Typical radiographic findings in patients with tetralogy of Fallot include a normal-sized heart, rounding of the right ventricular border, pulmonary vascular undercirculation, and hyperlucency of the lung field. The heart in humans with tetralogy of Fallot often displays a distinctive boot-shaped, or...
Oxford Univ Press (全网免费下载) mendeley.com drheart.net (全网免费下载) 相似文献 参考文献Long-Term Results of Total Repair of Tetralogy of Fallot in Adulthood: 35 years Follow-up in 104 Patients Corrected at the Age of 18 or Older* Long-term survival after surgical repair of tetralogy of...
Rare genetic variants in KDR, encoding the vascular endothelial growth factor receptor 2 (VEGFR2), have been reported in patients with tetralogy of Fallot (TOF). However, their role in disease causality and pathogenesis remains unclear. We conducted exom
To assess exercise tolerance and determine the distinct role of cardiac, respiratory, or peripheral factors on it after delayed surgical repair in patients with tetralogy of Fallot The aerobic exercise capacity of 15 adult patients (mean [± SD] age, 21 ± 6; age range, 9 to 30 years) unde...
nature publishing group Translational Investigation Articles Genetic determinants of right-ventricular remodeling after tetralogy of Fallot repair Aamir Jeewa1, Ashok Kumar Manickaraj1, Luc Mertens1, Cedric Manlhiot1, Caroline Kinnear1, Tapas Mondal2, John Smythe3, Herschel Rosenberg4, Jane Lougheed5,...
Hypoxia-inducible factor (HIF1A) regulates the myocardial response to hypoxia and hemodynamic load. We investigated the association of HIF1A variants with right-ventricular (RV) remodeling after tetralogy of Fallot (TOF) repair. Children with TOF were ge
NKX2-5, GATA4 and HAND1 are essential for heart development, however, little is known regarding their epigenetic regulation in the pathogenesis of tetralogy of fallot (TOF). Methylation levels were measured in three regions of NKX2-5 (M1: -1596 bp