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N.: The mechanism of action of tetanus toxin: Effect on synaptic processes and some particular features of toxin binding by the nervous tissue. Naunyn-Schmiedeberg's Arch. Pharmacol.276, 247–270 (1973) Google Scholar Kryzhanovsky, G. N., Kasil, G. N., Grafova, V. N., Pukhova, ...
The Mechanism of Action of Tetanus and Botulinum Neurotoxins Tetanus and botulinum neurotoxins were identified about a century ago as the cause of the neuroparalytic syndromes of tetanus and botulism (Faber, 1890; Ti... C Montecucco,G Schiavo - 《Molecular Microbiology》 被引量: 1143发表: 1994...
changes in brain and cord cells of tetanus-intoxicated animals are non-specific, and are slight, or frequently absent in humans4, any information concerning the binding of the toxic agent to specific cell structures might prove helpful in understanding the mechanism of its neurotoxic action....
The Mechanism of Action of Tetanus and Botulinum Neurotoxins Tetanus and boulinum-B neurotoxin block neurotransmitter release by a proteolytic cleavage of synapto-brevin Maternal Immunization with Influenza or Tetanus Toxoid Vaccine for Passive Antibody Protection in Young Infants ...
Tetanus toxin has a unique mechanism of action (Fig. 34-1). In a manner similar to the botulinum neurotoxins, tetanus toxin is initially bound at the presynaptic terminals of the neuromuscular junction. Unlike botulinum neurotoxin, it is then transported by motor neurons to the spinal cord. In...
Tetanus toxin has a unique mechanism of action that has direct impact for potential therapeutics (Bleck, 1991). Tetanus toxin, unlike the related and widely used therapeutic botulinum neurotoxin, is transported by motor neurons to the spinal cord (Schwab et al., 1979). In the spinal cord, te...
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