Trismus is the presenting sign in most cases, and sustained trismus produces a characteristic sardonic smile (i.e., risus sardonicus). Persistent contraction of the chest and back muscles presents as opisthotonus. Restlessness and irritability may be followed by tetanic seizures, often precipitated ...
It is characterized by cranial nerve palsies (especially the seventh) and leads to paralysis; it is associated with a high mortality. The most common type is generalized tetanus which is responsible for 80% of cases. It results from the haematogenous spread of the toxin. The muscles of the ...
Opisthotonus could be elic- ited with mild palpation of the paraspinal muscles. No tightening of facial muscles (risus sardonicus) nor signs of meningism were present clinically. He was admitted to the intensive care unit (ICU) and intubated. A clinical diagnosis of generalized tetanus was ...
摘要: Author information: (1)Laboratory for Infection Control, Graduate School of Medicine, Osaka University.关键词:Tetanus Clostridium Tetani Muscle Contractions Neck Muscles Exotoxins DOI: doi:10.1016/S0022-3476(47)80034-4 年份: 1934 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Europe PMC ...
Tetanic contraction happens when a continuous muscle contraction is produced by its motor neuron, which stimulates the muscle to the maximum to maintain the posture for a prolonged period. Tetanic-induced muscle contraction has abnormal characteristics such as preactivation in th...
Atetanusbooster shot may be required if a wound is deep or dirty. 但如果伤口很深或很脏的话,需要接种破伤风加强剂. 期刊摘选 The authors described their experience in nursingtetanuspatients treated by intracerebral injection oftetanusantitoxin.
muscles, including the diaphragm, leading to death (Sobel2005). Respiratory and skeletal muscle paralysis is accompanied by impairment of autonomic cholinergic nerves and of the myenteric nervous system with associated symptoms. Mild forms of botulism frequently go undetected and even more severe forms ...
A- Because of the risk of Guillain Barre syndrome B- Because it will increase the child's risk for bleeding, and kids fall down and scrape themselves all the t In extreme cases of untreated tetanus infections, patients will break bones and tea...
We found that even with careful low volume injection (0.2鈥 1.0 渭l) into a single muscle (medial gastrocnemius), the TTC hybrid proteins spread rapidly to many other hindlimb muscles and to trunk musculature such that retrograde labeling of motoneurons could not be constrained to a single ...
The pattern of toxin spread from the site of its elaboration to either nearby muscles or to the systemic circulation, as well as the relative susceptibility of motor neurons and muscles to the action of the toxin, likely accounts for the patterns of localized, generalized, or cephalic tetanus ...