Other studies have examined the role of perinatal conversion of testosterone to estradiol (aromatization) and actions via estradiol receptors vs. direct actions of testosterone or its androgenic metabolite, dihydrotestosterone, on neural androgen receptors in the control of the above-named functions ...
Testosterone is converted to estradiol by the activity of the aromatase enzyme, thus potentially increasing the risk of breast cancer recurrence. The use of AIs, however, may prevent such conversion and provide safety for this strategy. Prompted by this unmet need, we conducted a pilot study ...
SI conversion factors: To convert testosterone to nanomoles per liter, multiply by 0.0347; to convert free testosterone to picomoles per liter, multiply by 3.47; to convert estradiol to picomoles per liter, multiply by 3.67. Figure 3. Effects of Testosterone or Placebo Treatment for 12 Months ...
Now, compare these numbers with the reference ranges for estradiol (also measure by mass spectrometry): [9] * Pre-menopausal women in follicular, mid-cycle, and luteal phases of cycle: 2.4 pg/mL,3.1 pg/mLand 2.6 pg/mL, respectively; ...
In any case, this result indicates that high-T participants might have been better able to override defensive retaliatory responses, although the effect of T on aggression might be better explained by other factors such as testosterone-to-estradiol aromatization73,74 than by amygdala reactivity alone...
Higher concentrations of intracellular T and estradiol in obese SAT were also observed (2.4 vs. 1.3 ng/g, p = 0.013 and 0.075 vs. 0.22 ng/g, p = 0.004, respectively). Testosterone accumulation resulted in even lower expression in androgen-responsive genes involved in lipoly...
Yes on the man-test vs woman-man-test issue. It is true that Indole-3-Carbinol, which has anti-cancer effects, induces cytochrome P450-dependent metabolism of estradiol, which increases 2-hydroxylation and thereby inactivates of estrogens . However, these data comes from cell culture (in vitro...
In this non-controlled investigation, 5 obese women took 400 mg of purified I3C every day for 2 months. At the end of the study, all of the women had significant increases in estradiol 2-hydroxylation, i.e., the breakdown of an estrogen hormone. ...
The influence of these hormones in this study is likely limited, because the women were investigated during their follicular phase when progesterone and estradiol concentrations are lowest and similar to those in men. In addition, testosterone levels are also relatively low during the follicular phase...
Given the structure of our asset market, traders who accept or submit aggressive bids (high buying prices) or asks (low selling prices) more frequently will execute a higher number of transactions because their bids and asks will be preferentially selected by other traders. Thus, the number of...