We performed a cross-sectional study to verify whether endogenous testosterone levels are correlated with markers of inflammation and endothelial function and with anthropometric and metabolic profile in 53 pos
Cardiovascular disease is the leading cause of death in postmenopausal women. Women who have hysterectomies are three times more likely to develop cardiovascular disease compared to women who have not had one. Women who have hysterectomies generally receive estrogen replacement therapy but not testosteron...
Testosterone cannot be viewed as a clear-cut answer for women with HSDD; long-term side effects and risk for breast cancer remain uncertain. Summary Hypoactive sexual desire disorder (HSDD) is common in postmenopausal and oophorectomized women and is characterized by absent desire for sexual acti...
(Androderm, Testim) has not shown any benefit in the treatment ofvasomotorsymptoms. It has potentialadverse effects, including negative effects on the lipid parameters,clitoromegaly,hirsutism, and acne.32Testosterone is not recommended for the treatment ofhot flashes. For somepostmenopausal women, it...
Testosterone therapy in womenhas become a hot-button problem issue as women begin to realize the risk oflow testosteronelevels dropping with age for women and men. Testosterone therapy is used to treat the symptoms of testosterone deficiency in perimenopause, premenopause, and postmenopausal women, ...
Furthermore, endogenous testosterone levels are close to, or even higher than, cir- culating estrogen levels in postmenopausal women [19]. Preclinical studies have demonstrated testosterone's neu- roprotective effects [20, 21], such as supplemental testos- terone increasing spine synapses in the ...
All androgen levels for the women were lower than age-matched control groups found in the literature. The decreased DHEA-S levels suggest a a defect in adrenal steroidogenesis, which was seen in both premenopausal and postmenopausal women. Possible defects in regulatory mechanisms of adrenal ...
levels Delay in the onset of male puberty Metastatic inoperable breastcancerinpostmenopausalwomen; testosterone counteracts estrogen’s effects in hormone-sensitive breast cancer Testosterone has an orphan designation and is being investigated for use in: ...
Decreasing the levels of estrogens in postmenopausal women could be an effective approach to control hormone-sensitive breast cancer. Aromatase inhibitors are very effective in cancer treatment. They were developed starting with aminoglutethimide (28.4.23), which was considered a first-generation ...
It is not surprising that many clinical studies on sexual dysfunction have investigated the effect of chronic testosterone treatment on sexual behavior, especially in postmenopausal women because of their drop in endogenous testosterone levels. Routes of testosterone administration (with or without estrogen...