Testosterone has been tested by subcutaneous injection and implantation in mice and rats. In mice, the implant induced cervical- uterine tumors, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility ...
As the testicular interstitium is the dominant site of MLKL expression, we assessed how TSZ injection affected the most abundant interstitial immune cell type—the testicular macrophage [27]. There are two populations of testicular macrophages: one situated throughout the interstitial space and one bor...
Male bedding was given the 2nd week after BrdU injection (d7–d14), and as a focal stimulus 90 min before perfusion. The behaviour of the GDX mice was assessed one week before TST/oil treatment and at the end of the treatment (d16). (B) Olfactory preference behaviour indicates no ...
The date of the first pharmacy prescription or injection procedure code following the washout period was considered the index date for the new-user cohorts.14 Owing to a potential for differential adherence and discontinuation between the dosage forms (injections are administered every several weeks and...
3d). A linear correlation was evident between serum testosterone levels (either endogenous or induced by injection) and TACR3 expression in the hippocampus (Fig. 3e). Notably, administration of the TACR3 inhibitor osanetant (5 mg/kg) significantly reduced serum testosterone levels within 24 ...
Testosterone has been tested by subcutaneous injection and implantation in mice and rats. In mice, the implant induced cervical-uterine tumors, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility to...