Testosterone Levels in Prostate Cancer: Racial influencePoage, Wendy
Testosterone replacement therapy in older men with decreased or low-normal testosterone levels has been recognized to improve sexual function, increase lean body mass and decrease fat mass, improve exercise-induced coronary ischemia, and elevate mood, among other benefits. Prostate cancer remains the ...
The researchers found that prostate cancer cells are hardwired with a system that allows them to proliferate when the levels of testosterone are very low. But whenhormone levelsare elevated to resemble those present in the normal prostate, the cancer cells differentiate. "For decades, the goal of...
For this reason a study of the metabolism of testosterone in the normal rat prostate is being undertaken which, it is hoped, will be relevant to our other studies on the culture of human prostatic cancer. Data is also presented concerning the effect of cyproterone on testosterone metabolism in...
Prostate cancerThe widely accepted absolute contraindication for administration of testosterone in hypogonadal men with prostate cancer has been questioned. Although recommendations from some professional associations still adhere to the traditional concepts, there is increasing relaxation of such positions. ...
A researcher who found that testosterone raised the risk of prostate tumors and exacerbated the effects of carcinogenic chemical exposure in rats is urging caution in prescribing testosterone therapy to men who have not been diagnosed with hypogonadism,
The use of testosterone therapy in men with prostate cancer was previously contraindicated, although recent data challenge this axiom. Over the past 2 decades, there has been a dramatic paradigm shift in beliefs, attitude, and treatment of testosterone deficiency in men with...
Low androgen levels in men are associated with increased cardiovascular risk, through unclear mechanisms. We measured arterial stiffness (''compliance'') in 21 men receiving complete testosterone suppression therapy for prostate cancer, and in 25 controls. Systemic arterial compliance (SAC), which asses...
Although testosterone is often considered to be a catalyst of prostate cancer, a recent study suggests that the hormone may be able to subdue advanced prostate cancer and break down resistance to testosterone-blocking drugs used to treat the disease. ...
Pretreatment total testosterone was an independent predictor of extraprostatic disease in patients with localized prostate cancer. As testosterone decrease... R Tiguert,BA Inman - 《Journal of Urology》 被引量: 423发表: 2003年 Testosterone as a predictor of pathological stage in clinically localized ...