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Grouping samples with low prevalence of positives into pools and testing these pools can achieve considerable savings in testing resources compared with individual testing in the context of COVID-19. We review published pooling matrices, which encode the
The effective management of the coronavirus disease 2019 (COVID-19) pandemic depends on the bedrock of rapid and accurate testing to enable promptness in quarantining, contact tracing, epidemiologic characterization, evaluating vaccine response, and stra
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Applied methods were feasible with expected turnaround times for transport and laboratory diagnostics. Pooled RT-qPCR test results were communicated during the day of sampling in all cases. For groups with higher numbers of pooled tests due to splitting of classes into two test groups, a total ...
(and thus robustness) in laboratory implementation; pools are easy to form and putative positives are simply the individuals in positive pools. Indeed, several early proposals4,5,6,7for COVID-19 pooled testing focus on Dorfman testing. However, it is well-known that Dorfman testing can have ...