Genetic testing for the BRCA1 gene is available commercially and clinically. The information gained from this test impacts not only on the individual tested, but on family members as well. The test can offer an individual and their family the opportunity to gain valuable information about their ...
BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair BRCA1 and BRCA2 are tumor suppressor genes, familial mutations in which account for 5% of breast cancer cases in the USA annually. Germ line mutations in B... PJ O'Donovan,...
Patients with a higher likelihood to develop BRCA 1 or BRCA 2 mutations are slipping through the cracks, making testing for these mutations a vital part of any breast cancer treatment plan. It’s important for their providers to test for BRCA1 and BRCA2 gene mutations in patients with...
3 ⅐ No. 2 Genetic testing for breast cancer: Where are health care providers in the decision process? Christine M. Velicer, MS1,2, and Stephen Taplin, MD, MPH2,3 Purpose: To identify BRCA1/2 knowledge, genetic testing intentions, and communication patterns in breast cancer survivors (...
Molecular testing for the BRCA1 and BRCA2 Ashkenazi Jewish founder mutations: a report on the College of American Pathologists proficiency testing surveys. The purpose of this study was to analyze laboratory performance on proficiency testing surveys offered jointly by the College of American ...
For some patients, a BRCA1/2 mutation has already been identified in a family member. For other patients, genetic testing, of a family member affected with breast and/or ovarian cancer, is suggested at the appointment. By 1 April 2006, members of a total of 54 families in which a BRCA...
Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing Mutations in the BRCA1 gene are associated with an increased risk of breast and ovarian cancer in carrier women. An understanding of behavioral responses t... Jeffrey,R.,Botkin,... ...
Little is known about how the breast cancer (BRCA) gene mutation affects women’s decision-making processes. I use a feminist standpoint lens to explore the process by which BRCA-positive women came to socially construct and understand their risk for developing breast and/or ovarian cancer and ...
Gene panel testing for hereditary breast cancer 作者:Winship Ingrid*; Southey Melissa C 来源:Medical Journal of Australia, 2016, 204(5): 188-+. DOI:10.5694/mja15.01335 摘要 Inherited predisposition to breast cancer is explained only in part by mutations in the BRCA1 and BRCA2 genes. Most fam...
The nation's biggest medical lab testing firm, Quest Diagnostics, plans to offer a test for BRCA gene mutations, which are linked to increase risk for breast and ovarian cancers. The test will be made available at the company's 2,100 testing centers throughout the country, which serve about...