Genetic Testing for Factor V LeidenCPT(R)* Codes83891 Molecular diagnostics; isolation or extraction of highly purified nucleic acid, each nucleic acid type (DNA or RNA)83892 Molecular diagnostics; enzymatic digestion, each enzyme treatment83896 Molecular diagnostics; nucleic acid probe, each83898 ...
Factor IIFactor V LeidenFVLProthrombinThrombophiliaWe report an 81-year-old female with a heterozygous factor V Leiden mutation who developed purpura fulminans. Digital necrosis, a characteristic clinical feature of purpura fulminans was prominent. Purpura fulminans is more common in children and adult ...
Methods: We consecutively enrolled patients under 45 years of age, with less than 3 CVRF, evaluated for VTE or ATE, women and men as a comparator. The control group consisted of healthy young women. A thrombophilia panel and genetic testing for Factor V Leiden (FVL), G20210A Prothrombin ...
When appropriate clinical care requires testing for the factor V Leiden allele, either direct DNA-based genotyping or a factor V Leiden-specific functional assay is recommended. Patients who test positive by a functional assay should then be further studied with the DNA test for confirmation and ...
Hopkins M, Hogarth S, Rodriguez Vet al, The role of patents in the development and clinical use of genetic tests. Final Report. Deliverable D3b. Case studies on the role of IP in the development and clinical use of genetic tests for Factor V Leiden, TPMT and HPV in the USA and EU.htt...
Factor V Leiden (factor V Arg506Gln), the genetic defect underlying resistance to activated protein C, is the most common risk factor for venous thrombosis... FR Rosendaal - 《Blood》 被引量: 897发表: 1997年 Activated protein C resistance (FV:Q506) and pregnancy. Activated protein C (APC...
Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systema... CONTEXT: Testing for genetic risks for venous thromboembolism (VTE) is common, but the safety and utility of such testing need review....
Inappropriate Testing and Treatment of Factor V Leiden and Other Heritable ThrombophiliasScott J. Parsons DO aSven R. Olson MD bThomas G. DeLoughery MD, MACP, FAWM bThe American Journal of Medicine
Genetic testing, epigenetics, molecular diagnosticsT231FREQUENCY OF FACTOR V LEIDEN MUTATION IN PATIENTS WITH ACTIVATED PROTEIN C RESISTANCE – STUDY INSERBIAN POPULATIONS. Obradovic 3, M. Stanojevic3, J. Djurovic2, A. Vuksanovic3, T. Tomic3, M. Sarkic3, G. Stamenkovic11 Institute for Biologica...
Resistance to activated protein C and factor V Leiden. Activated Protein C (APC) resistance, one of the most common genetic risk factors for venous thrombosis, is caused by a single base mutation (G1691-->A) in the factor V (FV) gene resulting in the replacement of Arg506 by Gln at ...