she is still at higher risk for breast cancer than the general population due to the risk factor of having multiple family members with breast cancer. Another possibility with genetic testing is that a non-typical alteration in a breast cancer-related gene is ...
Background: This study aimed to evaluate the implementation of the population- and family history (FH) -based screening for BReast CAncer (BRCA) in Iran, a country where less than 10% of breast cancer cases are attributable to a gene mutation. Methods: This was a...
Reports on the difficulties in testing for the hereditary BRCA1 breast cancer gene. Discovery of different disease-causing mutations along the length of BRCA1; Failure of tests on women with cancer; Randomness of ...
The most commonly used gene expression profile test used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers led by Georgetown Lombardi Comprehensive Cancer Center. Their study, published in theJournal of Clinical Oncology("Cost-Effectiven...
HOLLYWOOD, Florida — The National Comprehensive Cancer Network (NCCN) only endorses one genomic test for use in patients with early-stage breast cancer, according to a presenter here at the NCCN 20th Annual Conference. Oncotype DX, a 21-gene assay from Genomic Health, has won that honor, sa...
Breast cancer is the most prevalent cancer among women (Siegel, Naishadham & Jemal, 2012). For decades, public health resources and campaigns have been dedicated to early detection and education (Lee et al., 2014) to women in high-risk groups. TheBRCA1andBRCA2gene mutations, for example, ...
Sandra van Dijk, M.A., Ph.D., of Leiden University Medical Center, The Netherlands, assessed psychological adjustment in 215 women who underwent DNA testing for BRCA gene mutations associated with hereditary breast cancer. Of these, 147 women—more than two-thirds of the total—had inconclusive...
摘要: Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to have chemotherapy, but many of them do not fully understand what some of the test results mean, new research suggests.
This breakthrough discovery directed researches to examine role of miRNA in cancer since miRNAs are involved in the development, cell differentiation, and ... Y Tutar - 《Current Pharmaceutical Biotechnology》 被引量: 93发表: 2014年 High prevalence of mutations in the dihydrofolate reductase gene of...
Breast and ovarian cancers are scary, anxiety-provoking diseases, and with good reason. Although breast cancer isn’t the cancer that kills the most women (lung …