For a series of amphoteric amino acid derivatives, we have demonstrated the ability to hydrolyze the tert-butyl ester functionality in protic solvent systems. Using a continuous plug flow reactor at 120-240掳C and 15-40min reaction times, no pH modification or additional reagents are needed to ...
DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly. DOTA tert-Butyl ester is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实...
产品编号 T19293 别名DO3A-t-Bu-ester, DO3A tert-butylCas号 122555-91-3 DOTA tert-butyl ester is a phenyl derivative of cycloteramide; it can be directly nitrated; it is more convenient to add nitro after deprotection of lithium aluminum hydride....
(alkyl = Et, Bn,iPr,tBu) by treatment with KOtBu intBuOH gives the corresponding 1,2-anti-2,3-anti-3-alkyl-β-amino esters in quantitative yield and in >98% de, with subsequent deprotection by hydrogenolysis and ester hydrolysis giving the corresponding 1,2-anti-2,3-anti-3-alkylcis...
Common alkylating agent. Used in the synthesis of the collagenase inhibitor (S,S,R)-(-)-actinonin. Building block for substituted t-butyl acetates. Employed in the synthesis of a dihydropyranyl prelinker which was used, in turn, in an efficient polymer-assisted deprotection of oligosacchararide...
Scandium Trinflate as an Efficient and Recyclable Catalyst for the Deprotection of Tert-Butyl Aryl Sulfonamides Scandium triflatesulfonamidedeprotectioncatalystA mild and efficient method for deprotection of tert-butyl sulfonamide groups utilizing Sc(OTf)_3- as de... WM Alterman - 《Synthetic Communicatio...
Deprotection of 513 with trifluoroacetic acid (TFA) followed by N-Cbz formation generated acid 514, which was subjected to Suárez's conditions for decarboxylation to give 515.185 Sequential DIBAL-H reduction and Wittig olefination provided α,β-unsaturated ester 516. A Pd-catalyzed hydrogenation/...
3) N-tertbutyloxycarbonyl-L-aspartic acid-β-benzylester N-叔丁氧羰基-L-天冬氨酸-β-苄酯 1. Cyclo(L-Asp-L-Pro) were synthesized from protected N-tertbutyloxycarbonyl-L-aspartic acid-β-benzylester and L-proline methyl ester hydrochloride via DCC condesation, deprotection of tert...
Target molecules were prepared through peptide coupling of the respective ring A building blocks with cis-5-vinylproline tert-butyl ester and subsequent ring-closing metathesis. Selective deprotection of a tert-butyl carbamate (N-Boc protecting group) in the presence of a tert-butyl ester was ...
Synonyms:(BOC)2O;(BOC)2O FLUKA;BOC;BOC ANHYDRIDE;tert-butyldicarbonate;PYROCARBONIC ACID DI-TERT-BUTYL ESTER;RARECHEM TB OC 0001;Boc Anhydride, solid/liquid CAS:24424-99-5 MF:C10H18O5 MW:218.25 EINECS:246-240-1 Product Categories:Pharmaceutical Intermediates;Starting Raw Materials & Intermedi...