Two new polyketides (1–2), four new norterpenoids (3–6), together with five known compounds (7–11) were isolated from the marine sponge Diacarnus megaspinorhabdosa. The new structures were determined by extensive spectroscopic analyses, ECD spectra comparison, and Mosher's method. The cyto...
putida as a host organism for the recombinant biosynthesis of such natural products, including rhamnolipids, terpenoids, polyketides and non-ribosomal peptides... A Loeschcke,S Thies - 《Applied Microbiology & Biotechnology》 被引量: 62发表: 2015年 Microbial transformations of sesquiterpenoids: convers...
Whereas polyketides and PKS-NRPS hybrid molecules occur in the stromata [1–6] and cultures of the family members [7, 8], terpenes were so far exclusively reported from cultures. Important examples of the latter structural class produced by the Xylariaceae are the antifungal sordarins from ...
Tsavoenones A-C: unprecedented polyketides with a 1,7-dioxadispiro[4.0.4.4]tetradecane core from the lichen: Parmotrema tsavoense Org. Biomol. Chem., 16 (32) (2018), pp. 5913-5919 View articleCrossrefView in ScopusGoogle Scholar [10] T.-H. Duong, M.A. Beniddir, G. Genta-Jouve,...
Figure 1. Structures of fungal polyketides synthesized by collaborative efforts of core enzymes. (A) Meroterpenoids derived from TC/ PKS, 6b−d etc. (B) Compounds derived from TC and NRPS enzymes, including ergokonin A 8a (proposed), aculene A, 9 and flavunoidine 1 (this study)....
Isoprenoids are the most numerous and structurally diverse family of natural products. Terpenoids, a class of isoprenoids often isolated from plants, are used as commercial flavor and fragrance compounds and antimalarial or anticancer drugs. Because plan
Two new polyketides (1-2), four new norterpenoids (3-6), together with five known compounds (7-11) were isolated from the marine sponge Diacarnus megaspinorhabdosa. The new structures were determined by extensive spectroscopic analyses, ECD spectra comparison, and Mosher's method. The cyto...
Recent Applications of Olefin Ring‐Closing Metathesis (RCM) in the Synthesis of Biologically Important Alkaloids, Terpenoids, Polyketides and Other Secondary Metabolitesorganic chemistry, reviewmetathesis reactionspharmacology, medicinal chemistry, vaccines, serums...
New alpha-hydroxy-ketone derivatives, useful as intermediates for biologically active polyketides, terpenoids, epothilones and their derivativesalpha -Hydroxy-ketone (acyloin) compounds (I), in non-racemic, optically active or racemic form at the alpha -hydroxy-position, and their hydroxy-protected ...
The electronic and hydrophobic parameters appeared to hold a conspicuous part in directing the antibacterial properties of the compounds. Seaweed-associated B.subtilis MTCC 10403 demonstrated to represent a potential source of antimicrobial polyketides for pharmaceutical applications. Copyright 2017 Elsevier ...