Gumbi PP, Jaumdally SZ, Salkinder AL, Burgers WA, Mkhize NN, Hanekom W, Coetzee D, Williamson A, Passmore JS: CD4 T cell depletion at the cervix during HIV infection is associated with accumulation of terminally differentiated T cells. J Virol 2011; 85:13333-13341....
High proportion of terminally differentiated regulatory T cells after allogeneic hematopoietic stem cell transplantationIt is now well-established that regulatory T cells (Treg) represent a heterogeneous group of CD4 T cells. Previous studies have demonstrated that Treg homeostasis was impacted by ...
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans Here we show that CCR4 was specifically expressed by a subset of terminally differentiated and most suppressive CD45RA-FOXP3(hi)CD4+ Treg cells [... D Sugiyama,H Nishika...
Altered proportions of naive, central memory and terminally differentiated central memory subsets among CD4+ and CD8 + T cells expressing CD26 in patients with type 1 diabetes. J Clin Immunol. 2011; 31 :977–84.MATTEUCCI E;GHIMENTI M;DI B S;.Altered proportions of naive,central memory and ...
High MHC-E expression on LN memory CD4+ T cells SIVagm-infected AGMs were thus characterized by an expansion of NKG2Alow cells in SLT. NKG2A is an inhibitory receptor that binds to a non-classical MHC type I, the MHC-E. Shaping of NK cell function via self-reactive inhibitory NK-cell...
Human Naive/Memory T Cell Panel Accumulation of memory T cells from childhood to old age: central and effector memory cells in CD4(+) versus effector memory and terminally differentiated memory cells in CD8(+) compartment. 2006; 127(3):274-281. (Biology)Seder RA... QT Human 被引量: 0...
the levels of stages 3 NK cells were negatively and positively correlated with replication competent virus in LN CD4+cells and the Env-specific NK cell activity, respectively (Fig.3j). These data imply that the terminally differentiated NKG2a/clowCD16+NK cells (stage 3) were responsible for th...
Reduced Central Memory CD4+ T Cells and Increased T-Cell Activation Characterise Treatment-Naive Patients Newly Diagnosed at Late Stage of HIV Infection We evaluated activation (expression of CD45R0 and CD38 on CD8+), sensitivity to Fas- mediated cells death (expression of CD95 on CD4+ and CD...
Tumor-infiltrating HBV-specific CD8+ T cells associate with prolonged patient relapse-free survival The observed correlation between the frequencies of liver antigen-specific and the CD8:CD4 ratio for T cell targeting HBV epitopes, but not for TA or bystander epitopes (Figure S2A), prompted us to...
2.Nouspikel T and Hanawalt PC. DNA repair in terminally differentiated cells.DNA repair.2002;1:59-75.. 3.Tichy ED and Stambrook PJ. DNA repair in murine embryonic stem cells and differentiated cells.Experimental cell research.2008;314:1929-36.. ...