Here we describe a unique property of the TWIST1 WR domain in mediating IL8 production and breast cancer cell invasion. Using Gene Set Enrichment Analysis (GSEA) of genetic profiles and cytokine array analyses, we found that IL8 was specifically up-regulated by TWIST1 over-expression in the hum...
Hou (Cancer Institute, Xuzhou Medical University, China). The DNA fragment of UPCP was inserted into the vector pET28a(+). Human BUBR1 shRNAs were cloned into pLKO.1 plasmid (pLKO.1-BUBR1#1 and pLKO.1-BUBR1#3). The sequences of shRNAs are described below: shCtrl_fwd (5′-CCGGA...
(resection) or infection removal). In some or any embodiments, the bone gap defect is produced by removal of infected sections of bone or the removal of cancer from the bone due to bone cancers including, but not limited to, osteosarcoma, Ewing's sarcoma, chondrosarcoma, malignant fibrous ...
Case Study: Prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised cancer patient Cell, 183 (2020), pp. 1901-1912.e9 View PDFView articleView in ScopusGoogle Scholar Barad et al., 2015 B.A. Barad, N. Echols, R.Y. Wang, Y. Cheng, F. DiMaio, P.D. Adams, J...
I think about my cancer sisters who have gone through radiation before me and I want to hug them tonight. I know what misery they went through. They are warriors. I think about all the women who will go through this after me, not just the radiation but all of it. They don’t yet ...
6B). We took advantage of the patient-derived xenograft system to explore the effect of BET inhibition on MYC expression in CAFs in vivo. The pathological structure of the xenograft tissues mimics the primary cancer tissues and the tumor stroma is obvious and easily identified in PDX. ...
Cancer Res., 49: 4682-9 (1989). Bost et. al., Antibodies against a peptide sequence within the HIV envelope protein crossreacts with human interleukin-2. Immunol. Invest., 17(6&7):577-86 (1988). Bostrom et. al., Ligand and signaling components of the transforming growth factor β...
Ubiquitin Carboxyl-Terminal Hydrolases and Human Malignancies: The Novel Prognostic and Therapeutic Implications for Head and Neck Cancer. Front. Oncol. 2021, 10, 592501. [Google Scholar] [CrossRef] [PubMed] Sharma, A.; Liu, H.; Tobar-Tosse, F.; Chand Dakal, T.; Ludwig, M.; Holz, ...
Metastasis is the primary cause of death for cancer patients. TWIST1, an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor, is a strong promoter of metastatic spread and its expression is elevated in many advanced human carcinom