Two weeks before hospitalisation, she had applied crotamiton/terbinafine cream on an area of itchy eruption on her right sole [ dosage not stated ]. However, her skin worsened at the application site. Physical examination revealed erythema and yellow crusts on her sole, along with scaly erythema...
Trade name(s) Lamisil Generic available No Drug class Allylamine antifungal agent Mechanism of action Inhibition of squalene epoxidase, which blocks ergosterol synthesis Dosage form 250 mg tablet; 1% cream Dermatologic indications and dosage See table Common side effects Cutaneous: skin eruption, ...
As a cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis).[1] Tablets by mouth are often prescribed for the treatment of onychomycosis, a fungal nail infection,...
Terbinafine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in drug dosage forms by UV spectrophotometry and high-performance thin layer chromatography (HPTLC). Definition ChEBI: A hydrochloride obtained by reaction of terbinafine with one molar equival...
The purpose of present research work was to develop a Film Forming Emulgel formulation of Terbinafine hydrochloride using carbopol 934 as a gelling agent for topical delivery with the aim to avoid hepatic first- pass metabolism, improve stability of emulsion, reduce dosage regimen and enhance ...
Terbinafine cream 1 % has also been well tolerated in clinical trials, with only 2% of patients experiencing adverse effects (local irritation, erythema, burning and dryness). Dosage and Administration The recommended adult dosage of oral terbinafine is 250mg daily (as a single or divided dose),...
An update of its use in superficial mycoses.Terbinafine is an allylamine antifungal agent which has fungicidal activity against a wide variety of dermatophytes, moulds and certain dimorphic fungi, and fungistatic activity against ...doi:10.2165/00003495-199958010-00018Karen J. McClellan...
The method was successfully applied to the analysis of TRH in its commercial tablets, cream, gel and spray formulations and the results were in good agreement with those obtained with the official method. In addition the method was also applied to the analysis of LNZ in its capsule and I.V...
mentagrophytes of other ITS genotypes strains that showed white cream to pale/dark brown pigmentation (Figure 2). In addition, the urease test on Christensen urease agar was positive for T. interdigitale and T. mentagrophytes ITS Type III* and Type VII after 3–5 days of incubation. On ...