Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. Coadministration of ...
Brand name: LamISIL Drug class: Allylamines - Squalene Epoxidase Inhibitors Chemical name: (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine hydrochloride Molecular formula: C21H25N CAS number: 78628-80-5Medically reviewed by Drugs.com on Apr 10, 2024. Written by ASH...
喜欢 0 阅读量: 23 作者: 陈昭姿 展开 年份: 1993 收藏 引用 批量引用 报错 分享 求助全文 通过文献互助平台发起求助,成功后即可免费获取论文全文。 请先登入 我们已与文献出版商建立了直接购买合作。 你可以通过身份认证进行实名认证,认证成功后本次下载的费用将由您所在的图书馆支付 您可以直接购买此...
TerbinafineTrade name(s)Trade NamesLamisilGeneric availableGeneric AvailableNoDrug classDrug ClassAllylamine antifungal agentMechanism of actionMechanismsInhibition of squalene epoxidase, which blocks ergosteroldoi:10.3109/14791130500070064Frances HumphreysJournal of Drug Evaluation...
Drug-Drug Interactions In vivostudies have shown that terbinafine is an inhibitor of the CYP450 2D6 isozyme. Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes:tricyclic antidepressants, selectiveserotoninreuptakeinhibitors, beta-blockers, antiarrhythmics class 1C...
Drug-Drug Interactions In vivostudies have shown that terbinafine is an inhibitor of the CYP450 2D6 isozyme. Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes:tricyclic antidepressants, selectiveserotoninreuptakeinhibitors, beta-blockers, antiarrhythmics class 1C...
It can be found both as a prescription and over-the-counter medication. As a brand name, it is sold under the name of Canesten. This drug is typically used two times per day for 2 to 8 weeks for skin infections and five times per day for two weeks for oral thrush. ...
Terbinafine demonstrates a good safety profile, and relatively few drug interactions have been identified. CONCLUSiONS: Terbinafine is more effective than the gold standard, griseofulvin, in the treatment of tinea pedis and tinea unguinum, with considerably shorter treatment duration in the latter. It...
Trade name(s) Lamisil Generic available No Drug class Allylamine antifungal agent Mechanism of action Inhibition of squalene epoxidase, which blocks ergosterol synthesis Dosage form 250 mg tablet; 1% cream Dermatologic indications and dosage See table Common side effects Cutaneous: skin eruption, ...
The present invention describes a synthesis method for the production of terbinafine and derivatives thereof. BACKGROUND ART Terbinafine, chemically defined as (E)-N-(6,6-dimethyl-2-hepten-4-inyl)-N-methyl-1-naphthalene-methylamine and having the structure (1), is an antimicotic drug for topi...