Thermes, "Ten years of next-generation sequencing technology," Trends in Genetics, vol. 30, no. 9, pp. 418-426, 2014.van Dijk, E. L., Auger, H., Jaszczyszyn, Y. & Thermes, C. Ten years of next-generation sequencing technology. Trends Genet. 30, 418-426 (2014)....
1、概述（摘要）2、Anoverviewoftenyearsofnext-generationsequencingtechnology3、Therevolution4、ImprovementsinNGSsamplepreparationmethodsanddataanalysisalgorithms5、AwidediversityofnovelNGSapplications 6、Concludingremarks 概述 NGS在过去十年中取得的巨大进展（读长、通量、成本等方面）广泛应用于基础科学以及临床医学、...
By contrast, long-read approaches provide read lengths that are well suited for de novo genome assembly applications and full-length isoform sequencing. NGS technologies have been evolving over the past 10 years, leading to substantial improvements in quality and yield; however, certain approaches ...
Ten years of next-generation sequencing technology Ten years ago next-generation sequencing (NGS) technologies appeared on the market. During the past decade, tremendous progress has been made in terms of s... EL Van Dijk,H Auger,Y Jaszczyszyn,... - 《Trends in Genetics》 被引量: 687...
Independent from this activity, there has been a major evolution of PGx research over the past 5 years that is driven by rapidly developing genomic tools. Innovative genotyping arrays and next-generation DNA sequencing (NGS) approaches are used to identify systematically rare variants and gene alt...
In such scenarios, the application of next-generation sequencing (NGS) on EV-DNA offers the distinct advantage, as it can identify unknown single nucleotide polymorphisms as well as detecting all classes of variants (structural variants such as insertions and deletions), which are primarily attributed...
In such scenarios, the application of next-generation sequencing (NGS) on EV-DNA offers the distinct advantage, as it can identify unknown single nucleotide polymorphisms as well as detecting all classes of variants (structural variants such as insertions and deletions), which are primarily attributed...
Dieses Verfahren eignet sich für die Analyse bestimmter Gene, die mittels NGS („next generation sequencing“) nicht vollständig untersucht werden können, außerdem zur gezielten Überprüfung bekannter familiärer Mutationen. Bei der Sanger-Sequenzierung können jedoch keine größ...
However, as our understanding better evolves over time, additional concerns such as tumor budding [12,13,14] and the concentration of ctDNA (circulating tumor DNA) measured by NGS (next-generation sequencing) have all gained significance in the risk assessment process [15]. The challenges ...
Next-generation sequencing technology has made the difference, and Zhang has been one of the most prolific at applying it; he and Holmes have reported thousands of new RNA viruses. Zhang has established a network of labs in China to try to monitor emerging viruses. He hopes to predict and ...