Temporal artery biopsy for diagnosing giant cell arteritis: the longer, the better? Ann Rheum Dis 2006;65:826-8.Mahr A, Saba M, Kambouchner M, et al. Temporal artery biopsy for diagnosing giant cell arteritis: the longer, the better? Ann Rheum Dis. 2006;65(6):826-828....
Biopsy of the temporal artery, a branch of the carotid artery, aids in the diagnosis of temporal arteritis. Histologic findings of granulomata, multinucleated giant cells, macrophages, lymphocytes, intraluminal thrombosis, and damaged blood vessel wall (including intima thickening) are diagnostic of te...
Although temporal artery biopsy (TAB) may be con-sidered a gold standard for the diagnosis of GCA, there issignificant debate over how accurately a definitive diag-nosis can
Histologic confirmation of the diagnosis with a temporal artery biopsy makes an important contribution to all 3 of these stages. A positive tissue diagnosis provides the clinician with the conviction to maintain high dosages of corticosteroids for a prolonged period, even if significant steroid-induced...
Aims: The aim of this paper was to identify the location and to grade the severity of most significant inflammation within positive temporal artery biopsies along with other key clinical and histologic characteristics. Methods: Charts and pathology slides for 70 patients diagnosed with temporal arteriti...
Archived formalin-fixed paraffin-embedded (FFPE) temporal artery biopsy (TAB) specimens potentially represent a valuable resource for large-scale genetic analysis of this disease. FFPE TAB samples were obtained from 12 patients with GCA. Extracted TAB DNA was assessed by real time PCR before ...
Murgatroyd H, Milne A: Positive temporal artery biopsy in a patient on therapeutic doses of steroids for six years. Eye 15:250--1, 2001Murgatroyd, H, Milne, A (2001) Positive temporal artery biopsy in a patient on therapeutic doses of steroids for six years. Eye 15: pp. 250-251...
giant cell panarteritis with mixed inflammatory cell infiltrate typical of juvenile temporal arteritis (JTA); another one, aged 40 years, who presented with headache and cerebral angiography consistent with an intracranial vasculitis and whose temporal artery biopsy confirmed an authentic multinucleated ...
How does previous corticosteroid treatment affect the biopsy findings in giant cell (temporal) arteritis? OBJECTIVE: To determine the effect of previous corticosteroid treatment on the results of temporal artery biopsy. DESIGN: Consecutive case series. SETTING:......
The diagnosis of classic giant cell temporal arteritis was established from the biopsy result. Postoperatively, the patient was treated with prednisone for 3 months. Three years after surgery, the patient remains well and reports no recurrence of temporal artery disease. Original language English (US...