Tavapadon met the primary endpoint in the pivotal Phase 3 TEMPO-2 flexible-dose monotherapy trial, demonstrating a statistically significant improvement from baseline in the MDS-UPDRS Parts II and III combined
We aimed to determine if intravenous tenecteplase improves outcomes in this subgroup of TEMPO-2 patients with disabling deficits. Methods: This was an exploratory secondary analysis of the TEMPO-2 trial, which randomized patients across 48 hospitals globally with minor acute ischemic stroke (NIHSS ...
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tempo time trial测试法是一种用于评估跑步者在中等强度下的耐力和速度的测试方法。它的目的是通过一定时间内以尽可能快的速度跑完一定距离来评估跑步者的临界速度和耐力水平。 2. tempo time trial测试法的步骤 (1)选择测试距离:根据跑步者的训练水平和目的,选择合适的测试距离,一般为3至5公里。 (2)热身:进行充...
The Three Clocks of Trial and Error Is Decision-Making Skill Trainable? Frictional and Structural Unknowns On Thinking Caps Personality Ambidexterity: Or How to Turn Yourself Inside-Out Inside the Miscellaneous Folder Coincidences and Correlations Lagrangian and Eulerian Decision-Making Extrovert-Introvert...
2.Bocci G,Francia G.Metronomic chemotherapy:pharmacology and clinical applications [M].Berlin Heidelberg:Springer-Verlag,2014:263-279. 3.Camerini A,Morabito A,Montanino A,et al.Final results of randomized phase Ⅱ trial ...
Methods:Single-joint readings of radiographic images of the hands/wrists and feet from patients in year 1 of the TEMPO trial (the methotrexate-only group [M] and the methotrexate+etanercept group [M+E]) were evaluated. Using the SvdH scoring, 2 readers blinded to treatment and true-time se...
2) Site Level Regulatory Documents ☐Executed Clinical Trial Agreement ☐Local Ethics Approval (relative amendments/correspondence)☐Approved Patient Consent Form/ Surrogate (if applicable)☐Signed Protocol Acceptance Letter ☐Local Lab Accreditation ☐Local Lab Normals/ Accepted Values ☐Ethics ...
automatically activated predominant response tendency needs to be suppressed with concurrent initiation of the context-appropriate response. While these mechanisms might occur too late in error trials, they may support successful performance in the next trial. Interestingly, studies focusing on error awarene...