Synonyms Thermosensitive hydrogels ; Thermally-sensitive hydrogels ; Intelligent gels Definition Temperature-sensitive hydrogels, which are part of the family of stimulus-sensitive hydrogels, consist of water-filled polymer networks (i. e., gels) that display a temperature-dependent degree of ...
水凝胶(hydrogels)是通过物理或化学交联形成的、具有三维网络结构的聚合物体系 , 与人体组织具有极其相似的物理特性 , 因此可作为一种重要的生物医用材料。现已被广泛用于药物递送、组织工程、组织黏合以及生物传感等领域。作为一种宏观载体 ,水凝胶可直接注射或植入到组织中,并于组织内形成稳定的药物储库 ,提高药物...
Thermo-sensitive hydrogels have also been demonstrated to be interesting formulations for the delivery of biotechnological drugs. Proteins and oligonucleotides can be loaded under mild conditions, stabilized, and released at a controlled rate. Finally, thermo-reversible polymers have been investigated for ...
Finally, to verify the suitability of these hydrogels as thermo-responsive devices, the drug release profiles were studied performing in vitro experiments around the swelling-shrinking transition temperatures of the macromolecular systems.doi:10.3109/10837450.2011.644298Spizzirri, Umile Gianfranco...
12.Design and Preparation of Temperature/pH Dual-Responsive Cross-linked Hydrogels交联型温度/pH双敏水凝胶的设计与制备 13.Renaturation of Proteins Assisted by Temperature-sensitive Poly(N-isopropyl Acrylamide) Hydrogel;温敏型聚N-异丙基丙烯酰胺凝胶协助蛋白质体外复性的基础研究 ...
Biodegradable pH/temperature-sensitive triblock copolymer hydrogels composed of poly(ethylene glycol) (PEG) and poly(尾-amino ester urethane) (PAEU) were s... TH Cong,SW Kang,L Yi,... - 《Soft Matter》 被引量: 49发表: 2011年 A Temperature-sensitive Hydrogel Refolding System: Preparation of...
Nasal delivery of cannabidiol inclusion complex temperature-sensitive hydrogels could effectively target to brains for the treatment of mice with post-traumatic stress disorder (PTSD), which is a novel promising option for the clinical treatment of PTSD. Download: Download high-res image (217KB) Down...
Thermo- and pH-sensitive hydrogels were prepared by graft copolymerization of N-isopropylacrylamide onto chitosan via γ-radiation . 采用γ辐射技术引发壳聚糖与N异丙基丙烯酰胺进行接枝共聚,制备了温度及pH敏感水凝胶。3) temperature/pH sensitive microgel 温度/pH敏感微凝胶4...
To date, there are many forms of commercially available hemostats, including sponges, powders, sheets, gauzes, and hydrogels, which exhibit effective hemorrhage control. But none of them, including the gold standard QuikClot Combat Gauze, can provide fast, temperature-sensitive treatment of hemorrhage...
A series of pH/temperature-sensitive hydrogels composed of maleilated chitosan (MC) and N-isopropylacrylamide (NIPAAm) were prepared and characterized with respect to their swelling behaviors, change of lower critical solution temperature (LCST). These hydrogels showed broad pH-sensitivities below 32 ...