MITOSIS, MEIOSIS, AND THE FORMATION OF GAMETES D TELOPHASE The last stage of mitosis, telophase, is in many ways the reverse of prophase. When the two sets of halved chromosomes have reached their destination,
We suspected that precocious MEN activation in nocodazole-treatedbub2Δcells causes activation of APC/C-Cdh1, leading to mitotic slippage. Indeed, a lack of Cdh1 markedly repressed sister-chromatid separation and nuclear division in nocodazole-treatedbub2Δcells (Figure2A, B). These observations clea...