1995. Barley telomeres are associated with two different types of satellite DNA se- quences. Chromosome Res. 3: 315-320.Brandes A, Roder MS, Ganal MW (1995) Barley telomeres are associated with two different types of satellite DNA se- quences. Chrom Res 3: 315±320....
TRF2 is the master shelterin factor: its depletion or the expression of a dominant negative form of TRF2, lacking the Myb and basic domains, trigger telomere end-to-end fusions. These chromosomal structures are a consequence of the activity of the DNA ligase IV and of the Non-Homologous End...
Telomeres are pivotal determinants of cell stemness, organismal aging, and lifespan. Herein, we examined similarities in telomeres ofArabidopsis thaliana, mice, and humans. We report the common traits, which include their composition in multimers of TTAGGG sequences and their protection by specialized...
Sign up with one click: Facebook Twitter Google Share on Facebook telomere (redirected fromTelomeres) Thesaurus Medical Encyclopedia tel·o·mere (tĕl′ə-mîr′, tē′lə-) n. Either of the sections of DNA occurring at the ends of a chromosome. ...
et al. Long telomeres are associated with clonality in wild populations of the fissiparous starfish Coscinasterias tenuispina. Heredity 115, 437–443 (2015). https://doi.org/10.1038/hdy.2015.43 Download citation Received30 September 2014 Revised23 March 2015 Accepted13 April 2015 Published20 May ...
These double strands form a loop structure, called a T loop, with a 3’G-rich single-stranded overhang at the end that inserts into the double-stranded DNA and returns to the telomere to form the so-called D loop [17] (Fig. 2). Telomeres are associated with 6 protein subunits, TRF1...
Telomeres are DNA repeats at the ends of the chromosomes that are important for maintaining genomic integrity by preventing erosion of the ends. Short telomeres in CLL have previously been shown to be associated with inferior prognosis however its prognostic relevance in chlorambucil based treatment has...
Human chromosomes are capped by telomeres, which consist of tandem repeats of DNA and associated proteins. The length of the telomeres is reduced with incr... L Paul,M Cattaneo,A D'Angelo,... - 《Journal of Nutrition》 被引量: 112发表: 2009年 Telomere shortening in human fibroblasts is ...
They found that shorter telomeres did seem to indicate a higher risk of developing Alzheimer's. Kuo says the researchers intend on following the participants in the UK Biobank study further, as the cohort is still relatively young (the oldest participants are about 80 years old now) with few ...
Cell divisions lead to the progressive erosion of telomeric repeats. When telomeres become too short to recruit the shelterin complex, they become dysfunctional, leading to telomere deprotection. Chromosome ends with dysfunctional telomeres are detected as sites of DNA damage, leading to the activation ...