The length of the r ...doi:10.1007/978-1-4614-8757-9_46-1Liliana Mancio-SilvaJose-Juan Lopez-RubioRhodes D, Giraldo R. Telomere structure and function. Curr Opin Struct Biol 1995; 5:311‑22.
Dynamics of Protein Binding to Telomeres in Living Cells: Implications for Telomere Structure and Function. Telomeric proteins have an essential role in the regulation of the length of the telomeric DNA tract and in protection against end-to-end chromosome fusion... Mattern,Karin,A.,... - 《...
Telomere Structure and FunctionDna, TelomericG, The
2Telomeres: Structure and function All cells have a programmed lifespan by which they synthesize, multiply and eventually completing their life span die off.Telomereslocated at the end of each chromosome are essential chromosomal elements, which ensure proper replication, protection of chromosome ends ...
The role of ATM in telomere structure and function. Ataxia telangiectasia (AT) is a rare human autosomal recessive disorder with a wide variety of phenotypic manifestations. AT patients are cancer prone and ... TK Pandita - 《Radiation Research》 被引量: 142发表: 2001年 The Role of ATM in...
Disruption of telomere structure and function in cancer cells is highly toxic as shown by detailed pre-clinical evaluation of telomerase inhibitors. Under telomerase inhibition, cells must divide sufficiently frequently to allow one or more telomeres to shorten to an unprotected length. Functioning ...
A very good, in-depth article that explains exactly the structure and function of telomeres.… March 30, 2017 What Are Telomeres And Why Should I Care? ,Telomeres in the news Janet Wojcicki and Elissa Epel, two leading professors at the University of California, San Francisco, discuss their ...
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously ‘invisible’ parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the ‘Ruminant T2T Consortium’ ...
Structure and Function of the Telomere Telomeres are specialized nucleoprotein structures found at the ends of linear chromosomes that guard against aberrant chromosomal rearrangements and preve... JE Johnson,D Broccoli - Humana Press 被引量: 2023发表: 2007年 ATM Prevents the Persistence and Propagation...
Furthermore, we demonstrate that oncogenic signalling, frequently associated with initiating cancer growth in humans, dramatically affected telomere structure and function by causing telomeric replication stress, rapid and stochastic telomere attrition, and consequently telomere dysfunction in cells that lack ...