In conclusion, the new cellular model mimics classical toxic TDP-43 cellular model and interestingly the toxicity of CTF25 is dependent on the proteasome.doi:10.1016/j.neuroscience.2014.09.043Liu, Y.Duan, W.Guo, Y.Li, Z.Han, H.Zhang, S....
The 25 kDa CTF binds to TDP-43 lacking the RNP2 motif.Shinnosuke TakagiYohei IguchiMasahisa KatsunoShinsuke IshigakiKensuke IkenakaYusuke FujiokaDaiyu HondaJunichi NiwaFumiaki TanakaHirohisa Watanabe
A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome. Neuroscience 281C, 88-98 (2014).Liu Y, Duan W, Guo Y, Li Z, Han H, Zhang S, et al. A new cellular model of pathological TDP-43: The neurotoxicity of ...
Effect of selected kinase inhibitors on aggregation of CTF-TDP-43-GFP (219–414).Diane, MoujalledJanine L., JamesSarah, J. ParkerGrace, E. LidgerwoodClare, DuncanJodi, MeyerowitzTakashi, NonakaMasato, HasegawaKatja, M. KanninenAlexandra, Grubman...