Improved long-term outcomes of patients with in‐ flammatory bowel disease receiving proactive compared with reactive monitoring of serum concentrations of infli- ximab[J]. Clin Gastroenterol Hepatol,2017,15(10): 1580-1588.e3. [21] VAUGHN B P,MARTINEZ-VAZQUEZ M,PATWARDHAN V R,et al. ...
Long-term TG therapy was effective and well-tolerated as a maintenance treatment for IBD in about 70% of patients, continuing TG during a median treatment time of more than 4 years. Adverse events were not uncommon, but were mainly tolerable and of limited severity. An approximate 6-TGN ...
纳入研究的文献类型有论著、综述、回顾性分析、病例分析、会议等。结论 由于抗真菌药在临床应用过程中个体差异大、联合用药易出现不良反应等,国内外对抗真菌药的TDM加大了关注。关键词:抗真菌药;TDM; 计量分析 Bibliometric analysis of research papers in the subject of TDM of antifungals CaoJiang1a, Baiyan1...
The results are clinically meaningful and highly statistically significant, said lead author Hans Wildiers, MD, PhD, a medical oncologist at KU Leuven in Belgium. SUGGESTED for you Dr Hans Wildiers The benefit was seen despite the fact that about half the patients in the T-DM1 group crossed ...
All long-term oral maintenance dose digoxin 0.125mg. to reach steady state after respectively in 0.5, 1, 2, 3, 6, 8, and 12 24h blood samples, serum digoxin concentrations were determined by fluorescence polarization immunoassay technology, the pharmacokinetics of package, the design and ...
一个多无线电终端(MultipleRadio Terminal, MRT)可同时包括长期演进(Long-Term Evolution, LTE)或先进长期演进(LTE-Advanced, LTE-A)无线电、无线局域网(Wireless Local Area Network, WLAN,如WiFi)接入无线电、蓝牙(Bluetooth, BT)无线电以及全球卫星导航系统(GlobalNavigation Satellite System, GNSS)无线电。
in addition, it can also be used as a stabilizer and antioxidant for the production of polyolefins such as polyvinyl chloride, polyethylene, and polypropylene; it can also be used to synthesize non-ionic surfactants, organic chemicals, fungicides, pesticides, lubricating oil additives, oilfield chemic...
Different industries have slightly different precise definitions of each term, as appropriate for the particular industry and application. However, a simple example demonstrates the difference. Your car is very reliable, but every 90 days (3000 miles) you take it in for service. Its availability ...
Relative to other transportation programs, most TDM agencies have negligible capital costs and operate using short-term (typically 1-2 year) funding horizons. As a result, many of these agencies have not previously been empowered to fully participate in long-range planning processes for their ...
Nevertheless, drug resistance, the persistence of cancer stem cells, and adverse drug effects still limit their ability to stabilize or cure malignant diseases in the long term. The main treatments for cancer involve surgery; pharmacological therapy, including chemotherapy; and/or radiation therapy. ...