PrEP在近些年的实践中显示出了显著的降低新发HIV感染的效果,但是PrEP的推广和普及仍然存在难度和挑战。 从高风险人群自身的因素出发,除了药物成本和药物可及性之外,药物的安全性也是影响他们PrEP意愿的一大因素,因此,关于安全性的科学依据,既需要在推广过程...
FTC/TDF对男男性行为者的 HIV暴露前预防(PrEP)非常有效,而顺性别女性使用FTC/TDF进行PrEP的实际有效性和依从性尚不清楚。2024年3月1日发表在JAMA杂志上一项研究,纳入来自6个国家的6296名顺性别女性,每日口服一次剂量FTC/TDF,根据依从性对...
BackgroundTenofovir/emtricitabine (TDF/FTC) used as pre-exposure prophylaxis (PrEP) has proven benefits in preventing HIV infection. Widespread use of TDF/FTC can only be justified if the preventative benefits outweigh potential risks of adverse events. A previous meta-analysis of TDF/FTC compared ...
规格:FTC200mg:TDF300mg-30片/瓶(盒) 参考:PrEP 索引:HIV/AIDS
Texas District Court Allows Employers to Deny HIV PrEP Coverage 30% of Cancer Deaths Linked to Smoking; Over-the-Counter Birth Control; and HIV and Premature Aging Recommended Reading Self Assessment Fast Five Quiz: Long-Acting Antiretroviral Therapy for HIV Infection Tables & Protocols HIV Tre...
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Adherence to daily, oral TDF/FTC PrEP during periconception among HIV-exposed South African womendoi:10.3389/frph.2023.1263422Hurwitz, Kathleen E.Isehunwa, Oluwaseyi O.Hendrickson, Kayla R.Jaggernath, ManjeethaKriel, YolandieSmith, Patricia M....
We compared two self-report measures (number of doses missed in past 7days and day-by-day past week pill taking) to results of tenofovir concentrations in dried blood spot (DBS) samples at quarterly visits over the first 12months of PrEP use. 1420 men and women in five US community ...
Background: HIV Prevention Trials Network (HPTN) 067/ADAPT evaluated tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) pre-exposure prophylaxis (PrEP) in women (South Africa) and men who have sex with men (Thailand, US). Participants received once-weekly directly observed therapy (DOT) of ...
Currently, there is no objective way to monitor PrEP adherence. Urine has been shown to be highly correlated with plasma tenofovir levels, with urine tenofovir levels >1000 ng/mL demonstrating recent (1-2 days) adherence to PrEP.Setting: This study was conducted at an urban community health ...