Medication adherenceDried blood spotsSelf-reportThe prevention effectiveness of oral preexposure prophylaxis (PrEP) is highly dependent on medication adherence but no validated longer term PrEP adherence measures are readily available for use by primary care clinicians caring for diverse populations. We ...
Of the three patients who had conserved-site substitutions (rtA87G, rtM/I204I, rtI233V) two were non-adherent to study medication; none were associated with tenofovir resistance in vitro (fold change <2). No TDF resistance was observed through 240 weeks of treatment. Download: Download high...
Primary objectives were retention at 48 weeks (in care at week 48 and completing >=50% of medication pickups) and adherence assessed by urine tenofovir levels. Risk behaviors and sexually transmitted infection diagnoses were also collected.Results: Seventy percent of participants were retained in ...
Strategies that identify and intervene with those challenged by adherence to daily medication are needed.Landovitz, Raphael J.Beymer, MatthewKofron, RyanAmico, Kathy RivetPsaros, ChristinaBushman, LaneAnderson, Peter L.Flynn, RisaLee, David P.Bolan, Robert K.Jordan, Wilbert C.Tseng, Chi-HongDi...
Presence/magnitude of symptoms (ACTG-HIV Symptom Index), quality of life (EQ-5D, EUROQoL & MOS-HIV), adherence (SMAQ), preference of treatment and perceived ease of medication (ESTAR) through 48 weeks were performed.Interim analysis of 125 patients with 16 weeks of follow up was performed...