The methods can be used to detect the TCR-γ gene rearrangement in acellular body fluid. The detection of TCR-γ gene rearrangement is useful in determination of clonality of T-cell population. The invention is useful in the diagnosis of lymphoproliferative disorder.Maher Albitar...
The SSCP imprint of PCR products is specific for each TCR-γ gene rearrangement, and may be used to evaluate concurrent/recurrent disease in individual patients.doi:10.1034/j.1600-0560.2000.027005228.xMichael MurphySabina SignorettiMarshall E. Kadin...
PCR gene rearrangementThe recombination events of the gamma and beta T-cell receptor (TCR) loci were analysed in a series of 39 peripheral T-cell lymphomas (PTCLs) in association with the expression of TCR chains. In TCR alpha beta PTCLs, 22/23 cases showed a gamma-gene rearrangement ...
参考文献 Chandler C Ho , Jack K Tung , James L Zehnder ,Bing M Zhang. Validation of a Next-Generation Sequencing-Based T-Cell Receptor Gamma Gene Rearrangement Diagnostic Assay: Transitioning from Capillary Electrophoresis to Next-Generation Sequencing. J Mol Diagn. 2021 Jul;23(7):805-815. EN...
[1]Garcia MJ, Martines-Delgado B,Granizo JJ,et al.IgH,TCR-gamma,and TCR-beta gene rearrangement in 80 B- and T-cell non-Hodgkin’s lymphomas:study of the association between proliferation and the so-called ‘aberrant’ patterns.Diagn mol Pathol,...
Rearrangement and expression of V~gamma1, V~gamma2 and V~gamma3 TCR gamma genes in C57BL/6 micePereira, P.Gerber, D.Regnault, A.Shu Ying HuangHermitte, V.Coutinho, A.Tonegawa, S.INTERNATIONAL IMMUNOLOGYPereira P, Gerber D, Regnault A, Huang SY, Hermitte V, Coutinho A et al. ...
2.Detection of Clonal T Cell Receptor γ Gene Rearrangement in Children with Acute Lymphoblastic Leukemia and Its Clinical Significance急性淋巴细胞白血病患儿T细胞受体γ基因重排的检测及临床意义 3.T Cell Receptor Gamma Gene Rearrangements in Mycosis Fougoides and B Cell Lymphoma;蕈样肉芽肿和B细胞淋巴瘤...
Dik WA, Pike-Overzet K, Weerkamp F, de Ridder D, de Haas EF, Baert MRet al. New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.J Exp Med2005;201: 1715–1723. ...
Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells Manuel Winter Elham Kashani Immo Prinz Immunology & Cell Biology (2014) Molecular mechanisms that control mouse and human TCR-αβ and TCR-γδ T cell development Tom Taghon Ellen V. Rothenberg Seminars...
Gene RearrangementGenes, T-Cell Receptor gammaMiddle AgedYasuda K, Matsuki Y, Kobari S, Matsuzaki J, Sato K, Nakanishi K.doi:10.1111/pin.12106Kazuyo YasudaDepartment of Pathology Japan Self‐Defense Forces Sapporo Hospital Sapporo JapanYasunori Matsuki...